[$^{3}$H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves
The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. After uptake, [$^{3}$H]adenosine is converted and retained primarily as [$^{3}$H]adenosine triphosphate...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1971-07, Vol.173 (3994), p.336-338 |
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| container_end_page | 338 |
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| container_issue | 3994 |
| container_start_page | 336 |
| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 173 |
| creator | Su, Che Bevan, John A. Burnstock, Geoffrey |
| description | The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. After uptake, [$^{3}$H]adenosine is converted and retained primarily as [$^{3}$H]adenosine triphosphate. Tritium is released from taenia coli treated with [$^{3}$H]adenosine upon activation of the nonadrenergic inhibitory nerves. These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves. |
| doi_str_mv | 10.1126/science.173.3994.336 |
| format | Article |
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After uptake, [$^{3}$H]adenosine is converted and retained primarily as [$^{3}$H]adenosine triphosphate. Tritium is released from taenia coli treated with [$^{3}$H]adenosine upon activation of the nonadrenergic inhibitory nerves. These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.173.3994.336</identifier><identifier>PMID: 4327032</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Adenine Nucleotides - analysis ; Adenine Nucleotides - metabolism ; Adenosine Triphosphate - biosynthesis ; Adenosine Triphosphate - metabolism ; Adenosine Triphosphate - physiology ; Adrenergics ; Animals ; Colon - drug effects ; Colon - innervation ; Colon - metabolism ; Cyclic AMP - metabolism ; Electric Stimulation ; Guinea Pigs ; Myenteric plexus ; Myenteric Plexus - physiology ; Nerves ; Nucleosides - pharmacology ; Time Factors ; Transmitters ; Tritium ; Tritium - analysis</subject><ispartof>Science (American Association for the Advancement of Science), 1971-07, Vol.173 (3994), p.336-338</ispartof><rights>Copyright 1971 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-c31a1b96f7bb04e8aa08ed084f60af5ef758d82c6bae4a50c1fd26ee15cfba263</citedby><cites>FETCH-LOGICAL-c419t-c31a1b96f7bb04e8aa08ed084f60af5ef758d82c6bae4a50c1fd26ee15cfba263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1732381$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1732381$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2884,2885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4327032$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Su, Che</creatorcontrib><creatorcontrib>Bevan, John A.</creatorcontrib><creatorcontrib>Burnstock, Geoffrey</creatorcontrib><title>[$^{3}$H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. 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These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves.</description><subject>Adenine Nucleotides - analysis</subject><subject>Adenine Nucleotides - metabolism</subject><subject>Adenosine Triphosphate - biosynthesis</subject><subject>Adenosine Triphosphate - metabolism</subject><subject>Adenosine Triphosphate - physiology</subject><subject>Adrenergics</subject><subject>Animals</subject><subject>Colon - drug effects</subject><subject>Colon - innervation</subject><subject>Colon - metabolism</subject><subject>Cyclic AMP - metabolism</subject><subject>Electric Stimulation</subject><subject>Guinea Pigs</subject><subject>Myenteric plexus</subject><subject>Myenteric Plexus - physiology</subject><subject>Nerves</subject><subject>Nucleosides - pharmacology</subject><subject>Time Factors</subject><subject>Transmitters</subject><subject>Tritium</subject><subject>Tritium - analysis</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMFLwzAchYMoc07_gwk9DG-tSZOmrbcxphOmgs6TaEjTX1xG19akFUT83-1Y0dM7fO-9w4fQmOCAkJBfOmWgVBCQmAY0TVlAKT9AQ4LTyE9DTA_REGPK_QTH0TE6cW6DccdSOkADRsMY03CI7l4mb9_0Z7J4neZQVs6U4K2sqdeVq9eygSvvEQqQDry8taZ8954as20L2Ziq9CrtzcsGrFHePdhPcKfoSMvCwVmfI_R8PV_NFv7y4eZ2Nl36ipG08RUlkmQp13GWYQaJlDiBHCdMcyx1BDqOkjwJFc8kMBlhRXQecgASKZ3JkNMRutj_1rb6aME1YmucgqKQJVStEzFLWYTZrsj2RWUr5yxoUVuzlfZLECx2FkVvUXQWxc6i6Cx2s_P-v822kP-Nem0dH-_5xjWV_f-MO5YQ-gvh6Xoa</recordid><startdate>19710723</startdate><enddate>19710723</enddate><creator>Su, Che</creator><creator>Bevan, John A.</creator><creator>Burnstock, Geoffrey</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19710723</creationdate><title>[$^{3}$H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves</title><author>Su, Che ; Bevan, John A. ; Burnstock, Geoffrey</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-c31a1b96f7bb04e8aa08ed084f60af5ef758d82c6bae4a50c1fd26ee15cfba263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Adenine Nucleotides - analysis</topic><topic>Adenine Nucleotides - metabolism</topic><topic>Adenosine Triphosphate - biosynthesis</topic><topic>Adenosine Triphosphate - metabolism</topic><topic>Adenosine Triphosphate - physiology</topic><topic>Adrenergics</topic><topic>Animals</topic><topic>Colon - drug effects</topic><topic>Colon - innervation</topic><topic>Colon - metabolism</topic><topic>Cyclic AMP - metabolism</topic><topic>Electric Stimulation</topic><topic>Guinea Pigs</topic><topic>Myenteric plexus</topic><topic>Myenteric Plexus - physiology</topic><topic>Nerves</topic><topic>Nucleosides - pharmacology</topic><topic>Time Factors</topic><topic>Transmitters</topic><topic>Tritium</topic><topic>Tritium - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Su, Che</creatorcontrib><creatorcontrib>Bevan, John A.</creatorcontrib><creatorcontrib>Burnstock, Geoffrey</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Su, Che</au><au>Bevan, John A.</au><au>Burnstock, Geoffrey</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>[$^{3}$H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1971-07-23</date><risdate>1971</risdate><volume>173</volume><issue>3994</issue><spage>336</spage><epage>338</epage><pages>336-338</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. After uptake, [$^{3}$H]adenosine is converted and retained primarily as [$^{3}$H]adenosine triphosphate. Tritium is released from taenia coli treated with [$^{3}$H]adenosine upon activation of the nonadrenergic inhibitory nerves. These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>4327032</pmid><doi>10.1126/science.173.3994.336</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1971-07, Vol.173 (3994), p.336-338 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74945046 |
| source | MEDLINE; Science Magazine; JSTOR Archive Collection A-Z Listing |
| subjects | Adenine Nucleotides - analysis Adenine Nucleotides - metabolism Adenosine Triphosphate - biosynthesis Adenosine Triphosphate - metabolism Adenosine Triphosphate - physiology Adrenergics Animals Colon - drug effects Colon - innervation Colon - metabolism Cyclic AMP - metabolism Electric Stimulation Guinea Pigs Myenteric plexus Myenteric Plexus - physiology Nerves Nucleosides - pharmacology Time Factors Transmitters Tritium Tritium - analysis |
| title | [$^{3}$H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves |
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