Effects of Subminimal Inhibitory Concentrations of Antibiotics in Experimental Infections

The antibacterial effects of subminimal inhibitory concentrations (sub-MICs) of antibiotics were studied in two animal models. In mice, the oral cephalosporin CGP 9000 was effective in 11 of 20 different gram-negative infections and cephalexin was effective in one of these infections, both at 50% ef...

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Veröffentlicht in:	Reviews of infectious diseases 1979-09, Vol.1 (5), p.862-879
Hauptverfasser:	Zak, O, Kradolfer, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Ampicillin - administration & dosage Animal models Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - blood Antibacterials Antibiotics Bacteria Bacterial Infections - blood Bacterial Infections - prevention & control Blood plasma Cephalexin - administration & dosage Cephaloridine - administration & dosage Cephalosporins Cephradine - administration & dosage Cephradine - analogs & derivatives Dosage Escherichia coli Escherichia coli Infections - microbiology Escherichia coli Infections - prevention & control Female Gentamicins - administration & dosage Infections Male Mice Proteus Infections - microbiology Proteus mirabilis Proteus mirabilis - cytology Rabbits Salmonella Infections - microbiology Salmonella typhimurium - cytology Significance of Subminimal Inhibitory Concentrations of Antibiotics Staphylococcal Infections - microbiology Staphylococcus aureus - isolation & purification
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