Ventilatory Strategies for Hypoxemia During Cardiac Surgery: Survey Validation for Anesthesiologists in Brazil

Perioperative hypoxemia is common in cardiac surgeries, and atelectasis is the main cause. Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anony...

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Veröffentlicht in:Revista brasileira de anestesiologia 2010-07, Vol.60 (4), p.406-414
Hauptverfasser: Parra, Celso Augusto Martins, Carmona, Maria José Carvalho, Junior, José Otávio Costa Auler, Malbouisson, Luiz Marcelo Sá
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container_issue 4
container_start_page 406
container_title Revista brasileira de anestesiologia
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creator Parra, Celso Augusto Martins
Carmona, Maria José Carvalho
Junior, José Otávio Costa Auler
Malbouisson, Luiz Marcelo Sá
description Perioperative hypoxemia is common in cardiac surgeries, and atelectasis is the main cause. Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anonymous questionnaire to observe ventilatory strategies for hypoxemia in cardiac surgeries adopted by five thousand anesthesiologists all over the country. Questionnaires were sent via e-mail for five thousand anesthesiologists in Brazil. Out of the questionnaires sent, 81 valid responses were received. Among the answers, 65 (80%) anesthesiologists use volume-controlled ventilation (VCV), while 16 (20%) prefer pressure-controlled ventilation (PCV). The tidal volume (Vt) used is lower than 10 mL.kg-1, for 46 (61%) versus 20 (30%) who adopt a Vt greater than 10 mL.kg-1. Forty-seven (58%) use PEEP and 15 (21%) use FiO2 above 60%. In the case of intraoperative hypoxemia, 20.9% increase or introduce PEEP, 70.3% increase the FiO2, 19.7% use alveolar recruitment maneuvers, 13.5% increase the tidal volume, and 20.9% check for the presence of failures in the anesthesia equipment. Responses were sent from 15 states. The conducts described in the questionnaires are compatible with those of the international literature. Adjusting the questionnaires format and the way to approach anesthesiologists, new studies could be undertaken. A hipoxemia perioperatória ocorre frequentemente em cirurgia cardíaca e a atelectasia é sua principal causa. Além disso, podemos citar como causas circulação extracorpórea (CEC), dissecção de artérias torácicas internas, status clínico prévio do paciente, entre outras. O presente estudo elaborou um questionário anônimo para observar as estratégias ventilatórias frente à hipoxemia em cirurgia cardíaca adotadas por cinco mil anestesiologistas distribuídos no país. Foram enviados questionários por e-mail a cinco mil anestesiologistas do Brasil. Dos questionários enviados, foram recebidas 81 respostas válidas. Dentre as respostas, 65 (80%) anestesiologistas fazem uso da ventilação controlada a volume (VCV) frente a 16 (20%) que preferem ventilação controlada à pressão (PCV). O volume (Vt) corrente utilizado é inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adotam um Vt maior que 10 mL.kg-1. Quarenta e sete (58%) usam PEEP e 17 (21%) utilizam FiO2 acima de 60%. No caso de hipoxemia intraoperatória, 20,9% aumentam ou introduzem PEEP, 70,3% aumentam
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Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anonymous questionnaire to observe ventilatory strategies for hypoxemia in cardiac surgeries adopted by five thousand anesthesiologists all over the country. Questionnaires were sent via e-mail for five thousand anesthesiologists in Brazil. Out of the questionnaires sent, 81 valid responses were received. Among the answers, 65 (80%) anesthesiologists use volume-controlled ventilation (VCV), while 16 (20%) prefer pressure-controlled ventilation (PCV). The tidal volume (Vt) used is lower than 10 mL.kg-1, for 46 (61%) versus 20 (30%) who adopt a Vt greater than 10 mL.kg-1. Forty-seven (58%) use PEEP and 15 (21%) use FiO2 above 60%. In the case of intraoperative hypoxemia, 20.9% increase or introduce PEEP, 70.3% increase the FiO2, 19.7% use alveolar recruitment maneuvers, 13.5% increase the tidal volume, and 20.9% check for the presence of failures in the anesthesia equipment. Responses were sent from 15 states. The conducts described in the questionnaires are compatible with those of the international literature. Adjusting the questionnaires format and the way to approach anesthesiologists, new studies could be undertaken. A hipoxemia perioperatória ocorre frequentemente em cirurgia cardíaca e a atelectasia é sua principal causa. Além disso, podemos citar como causas circulação extracorpórea (CEC), dissecção de artérias torácicas internas, status clínico prévio do paciente, entre outras. O presente estudo elaborou um questionário anônimo para observar as estratégias ventilatórias frente à hipoxemia em cirurgia cardíaca adotadas por cinco mil anestesiologistas distribuídos no país. Foram enviados questionários por e-mail a cinco mil anestesiologistas do Brasil. Dos questionários enviados, foram recebidas 81 respostas válidas. Dentre as respostas, 65 (80%) anestesiologistas fazem uso da ventilação controlada a volume (VCV) frente a 16 (20%) que preferem ventilação controlada à pressão (PCV). O volume (Vt) corrente utilizado é inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adotam um Vt maior que 10 mL.kg-1. Quarenta e sete (58%) usam PEEP e 17 (21%) utilizam FiO2 acima de 60%. No caso de hipoxemia intraoperatória, 20,9% aumentam ou introduzem PEEP, 70,3% aumentam a FiO2, 19,7% realizam manobra de recrutamento alveolar, 13,5% aumentam o volume-corrente e 20,9% realizam checagem de falhas no aparelho de anestesia. As respostas foram enviadas de 15 estados. As condutas descritas nos questionários respondidos são compatíveis com a literatura internacional. Com ajuste no formato do questionário e na abordagem aos anestesiologistas, novos estudos poderão ser realizados. La hipoxemia perioperatoria ocurre frecuentemente en la cirugía cardíaca, y la atelectasia es su principal causa. Además, podemos citar como causas la circulación extracorpórea (CEC), disección de arterias torácicas internas, status clínico previo del paciente, entre otras. El presente estudio elaboró un cuestionario anónimo para observar las estrategias ventilatorias frente a la hipoxemia en cirugía cardíaca adoptadas por cinco mil anestesiólogos en todo el país. Fueron enviados cuestionarios por e-mail a cinco mil anestesiólogos de Brasil. De los cuestionarios enviados, se recibieron 81 respuestas válidas. Entre las respuestas, 65 (80%) anestesiólogos usan ventilación controlada a volumen (VCV) frente a 16 (20%) que prefieren la ventilación controlada a presión (PCV). El volumen (Vt) corriente utilizado es inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adoptan un Vt mayor que 10 mL.kg-1. Cuarenta y siete (58%) usan PEEP y 17 (21%) utilizan FiO2 por encima del 60%. En el caso de hipoxemia intraoperatoria, 20,9% aumentan o introducen PEEP, un 70,3% aumentan la FiO2, un 19,7% realizan maniobra de reclutamiento alveolar, un 13,5% aumentan el volumen corriente y un 20,9% realizan el chequeo de fallas en el aparato de anestesia. Las respuestas fueron enviadas desde 15 estados. Las conductas descritas en los cuestionarios respondidos están a tono con la literatura internacional. 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All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-a28e4d77bb43f19072c61ab1c6f50012f6989ac65185de9c559ebeb79ee809aa3</citedby><cites>FETCH-LOGICAL-c360t-a28e4d77bb43f19072c61ab1c6f50012f6989ac65185de9c559ebeb79ee809aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0034709410700507$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,860,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20659613$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parra, Celso Augusto Martins</creatorcontrib><creatorcontrib>Carmona, Maria José Carvalho</creatorcontrib><creatorcontrib>Junior, José Otávio Costa Auler</creatorcontrib><creatorcontrib>Malbouisson, Luiz Marcelo Sá</creatorcontrib><title>Ventilatory Strategies for Hypoxemia During Cardiac Surgery: Survey Validation for Anesthesiologists in Brazil</title><title>Revista brasileira de anestesiologia</title><addtitle>Rev Bras Anestesiol</addtitle><description>Perioperative hypoxemia is common in cardiac surgeries, and atelectasis is the main cause. Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anonymous questionnaire to observe ventilatory strategies for hypoxemia in cardiac surgeries adopted by five thousand anesthesiologists all over the country. Questionnaires were sent via e-mail for five thousand anesthesiologists in Brazil. Out of the questionnaires sent, 81 valid responses were received. Among the answers, 65 (80%) anesthesiologists use volume-controlled ventilation (VCV), while 16 (20%) prefer pressure-controlled ventilation (PCV). The tidal volume (Vt) used is lower than 10 mL.kg-1, for 46 (61%) versus 20 (30%) who adopt a Vt greater than 10 mL.kg-1. Forty-seven (58%) use PEEP and 15 (21%) use FiO2 above 60%. In the case of intraoperative hypoxemia, 20.9% increase or introduce PEEP, 70.3% increase the FiO2, 19.7% use alveolar recruitment maneuvers, 13.5% increase the tidal volume, and 20.9% check for the presence of failures in the anesthesia equipment. Responses were sent from 15 states. The conducts described in the questionnaires are compatible with those of the international literature. Adjusting the questionnaires format and the way to approach anesthesiologists, new studies could be undertaken. A hipoxemia perioperatória ocorre frequentemente em cirurgia cardíaca e a atelectasia é sua principal causa. Além disso, podemos citar como causas circulação extracorpórea (CEC), dissecção de artérias torácicas internas, status clínico prévio do paciente, entre outras. O presente estudo elaborou um questionário anônimo para observar as estratégias ventilatórias frente à hipoxemia em cirurgia cardíaca adotadas por cinco mil anestesiologistas distribuídos no país. Foram enviados questionários por e-mail a cinco mil anestesiologistas do Brasil. Dos questionários enviados, foram recebidas 81 respostas válidas. Dentre as respostas, 65 (80%) anestesiologistas fazem uso da ventilação controlada a volume (VCV) frente a 16 (20%) que preferem ventilação controlada à pressão (PCV). O volume (Vt) corrente utilizado é inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adotam um Vt maior que 10 mL.kg-1. Quarenta e sete (58%) usam PEEP e 17 (21%) utilizam FiO2 acima de 60%. No caso de hipoxemia intraoperatória, 20,9% aumentam ou introduzem PEEP, 70,3% aumentam a FiO2, 19,7% realizam manobra de recrutamento alveolar, 13,5% aumentam o volume-corrente e 20,9% realizam checagem de falhas no aparelho de anestesia. As respostas foram enviadas de 15 estados. As condutas descritas nos questionários respondidos são compatíveis com a literatura internacional. Com ajuste no formato do questionário e na abordagem aos anestesiologistas, novos estudos poderão ser realizados. La hipoxemia perioperatoria ocurre frecuentemente en la cirugía cardíaca, y la atelectasia es su principal causa. Además, podemos citar como causas la circulación extracorpórea (CEC), disección de arterias torácicas internas, status clínico previo del paciente, entre otras. El presente estudio elaboró un cuestionario anónimo para observar las estrategias ventilatorias frente a la hipoxemia en cirugía cardíaca adoptadas por cinco mil anestesiólogos en todo el país. Fueron enviados cuestionarios por e-mail a cinco mil anestesiólogos de Brasil. De los cuestionarios enviados, se recibieron 81 respuestas válidas. Entre las respuestas, 65 (80%) anestesiólogos usan ventilación controlada a volumen (VCV) frente a 16 (20%) que prefieren la ventilación controlada a presión (PCV). El volumen (Vt) corriente utilizado es inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adoptan un Vt mayor que 10 mL.kg-1. Cuarenta y siete (58%) usan PEEP y 17 (21%) utilizan FiO2 por encima del 60%. En el caso de hipoxemia intraoperatoria, 20,9% aumentan o introducen PEEP, un 70,3% aumentan la FiO2, un 19,7% realizan maniobra de reclutamiento alveolar, un 13,5% aumentan el volumen corriente y un 20,9% realizan el chequeo de fallas en el aparato de anestesia. Las respuestas fueron enviadas desde 15 estados. Las conductas descritas en los cuestionarios respondidos están a tono con la literatura internacional. Nuevos estudios se podrán hacer ajustando el formato del cuestionario y el abordaje a los anestesiólogos.</description><subject>ANESTESIOLOGIA: Condutas na Prática Médica</subject><subject>Anesthesiology</subject><subject>ANESTHESIOLOGY: medical practice</subject><subject>Brazil</subject><subject>CIRURGIA, Cardíaca: circulação extracorpórea</subject><subject>COMPLICATIONS: atelectasis, hypoxemia</subject><subject>COMPLICAÇÕES: atelectasia, hipoxemia</subject><subject>Humans</subject><subject>Hypoxia - therapy</subject><subject>Intraoperative Complications - therapy</subject><subject>Practice Patterns, Physicians</subject><subject>SURGERY, Cardiac: extracorporeal circulation</subject><subject>Surveys and Questionnaires</subject><issn>0034-7094</issn><issn>1806-907X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQhi0EokvhJ4B8Aw6h43zYMRdUlo9WqsRhoeJmOc5kGZSNF9upSH89yW7bKydb1vN65n0YeyngnQAhzzYARZkp0OUbAW8VQAWZesRWogaZaVA_H7PVA3LCnsX4GyCXlYCn7CQHWWkpihUbrnFI1Nvkw8Q3KdiEW8LIOx_4xbT3f3FHln8aAw1bvrahJev4ZgxbDNP75XKDE7-2PbU2kR8OufMBY_qFkXzvtxRT5DTwj8HeUv-cPelsH_HF3XnKfnz5_H19kV19-3q5Pr_KXCEhZTavsWyVapqy6MTcJndS2EY42VUAIu-krrV1c5u6alG7qtLYYKM0Yg3a2uKUvT7-uw_-zzivY3YUHfa9HdCP0ahSQ14XUs1kdSRd8DEG7Mw-0M6GyQgwi2lzMG0WjcvTwbRZcq_uJozNDtuH1L3aGfhwBHDueUMYTHSEg8OWArpkWk__GfEPNwiPnA</recordid><startdate>201007</startdate><enddate>201007</enddate><creator>Parra, Celso Augusto Martins</creator><creator>Carmona, Maria José Carvalho</creator><creator>Junior, José Otávio Costa Auler</creator><creator>Malbouisson, Luiz Marcelo Sá</creator><general>Elsevier Editora Ltda</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201007</creationdate><title>Ventilatory Strategies for Hypoxemia During Cardiac Surgery: Survey Validation for Anesthesiologists in Brazil</title><author>Parra, Celso Augusto Martins ; Carmona, Maria José Carvalho ; Junior, José Otávio Costa Auler ; Malbouisson, Luiz Marcelo Sá</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-a28e4d77bb43f19072c61ab1c6f50012f6989ac65185de9c559ebeb79ee809aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>ANESTESIOLOGIA: Condutas na Prática Médica</topic><topic>Anesthesiology</topic><topic>ANESTHESIOLOGY: medical practice</topic><topic>Brazil</topic><topic>CIRURGIA, Cardíaca: circulação extracorpórea</topic><topic>COMPLICATIONS: atelectasis, hypoxemia</topic><topic>COMPLICAÇÕES: atelectasia, hipoxemia</topic><topic>Humans</topic><topic>Hypoxia - therapy</topic><topic>Intraoperative Complications - therapy</topic><topic>Practice Patterns, Physicians</topic><topic>SURGERY, Cardiac: extracorporeal circulation</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parra, Celso Augusto Martins</creatorcontrib><creatorcontrib>Carmona, Maria José Carvalho</creatorcontrib><creatorcontrib>Junior, José Otávio Costa Auler</creatorcontrib><creatorcontrib>Malbouisson, Luiz Marcelo Sá</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Revista brasileira de anestesiologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parra, Celso Augusto Martins</au><au>Carmona, Maria José Carvalho</au><au>Junior, José Otávio Costa Auler</au><au>Malbouisson, Luiz Marcelo Sá</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ventilatory Strategies for Hypoxemia During Cardiac Surgery: Survey Validation for Anesthesiologists in Brazil</atitle><jtitle>Revista brasileira de anestesiologia</jtitle><addtitle>Rev Bras Anestesiol</addtitle><date>2010-07</date><risdate>2010</risdate><volume>60</volume><issue>4</issue><spage>406</spage><epage>414</epage><pages>406-414</pages><issn>0034-7094</issn><eissn>1806-907X</eissn><abstract>Perioperative hypoxemia is common in cardiac surgeries, and atelectasis is the main cause. Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anonymous questionnaire to observe ventilatory strategies for hypoxemia in cardiac surgeries adopted by five thousand anesthesiologists all over the country. Questionnaires were sent via e-mail for five thousand anesthesiologists in Brazil. Out of the questionnaires sent, 81 valid responses were received. Among the answers, 65 (80%) anesthesiologists use volume-controlled ventilation (VCV), while 16 (20%) prefer pressure-controlled ventilation (PCV). The tidal volume (Vt) used is lower than 10 mL.kg-1, for 46 (61%) versus 20 (30%) who adopt a Vt greater than 10 mL.kg-1. Forty-seven (58%) use PEEP and 15 (21%) use FiO2 above 60%. In the case of intraoperative hypoxemia, 20.9% increase or introduce PEEP, 70.3% increase the FiO2, 19.7% use alveolar recruitment maneuvers, 13.5% increase the tidal volume, and 20.9% check for the presence of failures in the anesthesia equipment. Responses were sent from 15 states. The conducts described in the questionnaires are compatible with those of the international literature. Adjusting the questionnaires format and the way to approach anesthesiologists, new studies could be undertaken. A hipoxemia perioperatória ocorre frequentemente em cirurgia cardíaca e a atelectasia é sua principal causa. Além disso, podemos citar como causas circulação extracorpórea (CEC), dissecção de artérias torácicas internas, status clínico prévio do paciente, entre outras. O presente estudo elaborou um questionário anônimo para observar as estratégias ventilatórias frente à hipoxemia em cirurgia cardíaca adotadas por cinco mil anestesiologistas distribuídos no país. Foram enviados questionários por e-mail a cinco mil anestesiologistas do Brasil. Dos questionários enviados, foram recebidas 81 respostas válidas. Dentre as respostas, 65 (80%) anestesiologistas fazem uso da ventilação controlada a volume (VCV) frente a 16 (20%) que preferem ventilação controlada à pressão (PCV). O volume (Vt) corrente utilizado é inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adotam um Vt maior que 10 mL.kg-1. Quarenta e sete (58%) usam PEEP e 17 (21%) utilizam FiO2 acima de 60%. No caso de hipoxemia intraoperatória, 20,9% aumentam ou introduzem PEEP, 70,3% aumentam a FiO2, 19,7% realizam manobra de recrutamento alveolar, 13,5% aumentam o volume-corrente e 20,9% realizam checagem de falhas no aparelho de anestesia. As respostas foram enviadas de 15 estados. As condutas descritas nos questionários respondidos são compatíveis com a literatura internacional. Com ajuste no formato do questionário e na abordagem aos anestesiologistas, novos estudos poderão ser realizados. La hipoxemia perioperatoria ocurre frecuentemente en la cirugía cardíaca, y la atelectasia es su principal causa. Además, podemos citar como causas la circulación extracorpórea (CEC), disección de arterias torácicas internas, status clínico previo del paciente, entre otras. El presente estudio elaboró un cuestionario anónimo para observar las estrategias ventilatorias frente a la hipoxemia en cirugía cardíaca adoptadas por cinco mil anestesiólogos en todo el país. Fueron enviados cuestionarios por e-mail a cinco mil anestesiólogos de Brasil. De los cuestionarios enviados, se recibieron 81 respuestas válidas. Entre las respuestas, 65 (80%) anestesiólogos usan ventilación controlada a volumen (VCV) frente a 16 (20%) que prefieren la ventilación controlada a presión (PCV). El volumen (Vt) corriente utilizado es inferior a 10 mL.kg-1 para 46 (61%) contra 29 (39%) que adoptan un Vt mayor que 10 mL.kg-1. Cuarenta y siete (58%) usan PEEP y 17 (21%) utilizan FiO2 por encima del 60%. En el caso de hipoxemia intraoperatoria, 20,9% aumentan o introducen PEEP, un 70,3% aumentan la FiO2, un 19,7% realizan maniobra de reclutamiento alveolar, un 13,5% aumentan el volumen corriente y un 20,9% realizan el chequeo de fallas en el aparato de anestesia. Las respuestas fueron enviadas desde 15 estados. Las conductas descritas en los cuestionarios respondidos están a tono con la literatura internacional. Nuevos estudios se podrán hacer ajustando el formato del cuestionario y el abordaje a los anestesiólogos.</abstract><cop>Brazil</cop><pub>Elsevier Editora Ltda</pub><pmid>20659613</pmid><doi>10.1016/S0034-7094(10)70050-7</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects ANESTESIOLOGIA: Condutas na Prática Médica
Anesthesiology
ANESTHESIOLOGY: medical practice
Brazil
CIRURGIA, Cardíaca: circulação extracorpórea
COMPLICATIONS: atelectasis, hypoxemia
COMPLICAÇÕES: atelectasia, hipoxemia
Humans
Hypoxia - therapy
Intraoperative Complications - therapy
Practice Patterns, Physicians
SURGERY, Cardiac: extracorporeal circulation
Surveys and Questionnaires
title Ventilatory Strategies for Hypoxemia During Cardiac Surgery: Survey Validation for Anesthesiologists in Brazil
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