Serum antimullerian hormone (AMH) levels are elevated in adolescent girls with polycystic ovaries and the polycystic ovarian syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence accordi...
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| Veröffentlicht in: | Fertility and sterility 2010-08, Vol.94 (3), p.1118-1121 |
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| container_title | Fertility and sterility |
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| creator | Hart, Roger, M.D Doherty, Dorota A., Ph.D Norman, Robert J., M.D Franks, Stephen, F. Med.Sci Dickinson, Jan E., M.D Hickey, Martha, M.D Sloboda, Deborah M., Ph.D |
| description | Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement, avoiding more extensive and potentially more invasive investigations. The study failed to demonstrate, in a general adolescent population, that serum AMH is a reliable predictor of PCO morphology or for the presence of PCOS. |
| doi_str_mv | 10.1016/j.fertnstert.2009.11.002 |
| format | Article |
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Med.Sci ; Dickinson, Jan E., M.D ; Hickey, Martha, M.D ; Sloboda, Deborah M., Ph.D</creator><creatorcontrib>Hart, Roger, M.D ; Doherty, Dorota A., Ph.D ; Norman, Robert J., M.D ; Franks, Stephen, F. Med.Sci ; Dickinson, Jan E., M.D ; Hickey, Martha, M.D ; Sloboda, Deborah M., Ph.D</creatorcontrib><description>Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement, avoiding more extensive and potentially more invasive investigations. 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Obstetrics ; Humans ; Internal Medicine ; Medical sciences ; Non tumoral diseases ; Obstetrics and Gynecology ; Organ Size ; Ovarian Cysts - blood ; Ovarian Cysts - diagnosis ; Ovarian Cysts - pathology ; Ovary - pathology ; Polycystic Ovary Syndrome - blood ; Polycystic Ovary Syndrome - diagnosis ; Polycystic Ovary Syndrome - pathology ; Sensitivity and Specificity ; Up-Regulation</subject><ispartof>Fertility and sterility, 2010-08, Vol.94 (3), p.1118-1121</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2010 American Society for Reproductive Medicine</rights><rights>2015 INIST-CNRS</rights><rights>Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-c7cc8b585e6d58542f6fe15285f6d9ce16e84e3f749535fb6a15a8745fd3b1d43</citedby><cites>FETCH-LOGICAL-c458t-c7cc8b585e6d58542f6fe15285f6d9ce16e84e3f749535fb6a15a8745fd3b1d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028209039867$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23087542$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20060112$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hart, Roger, M.D</creatorcontrib><creatorcontrib>Doherty, Dorota A., Ph.D</creatorcontrib><creatorcontrib>Norman, Robert J., M.D</creatorcontrib><creatorcontrib>Franks, Stephen, F. 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The study failed to demonstrate, in a general adolescent population, that serum AMH is a reliable predictor of PCO morphology or for the presence of PCOS.</description><subject>Adolescent</subject><subject>Anti-Mullerian Hormone - blood</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - blood</subject><subject>Body Mass Index</subject><subject>Cohort Studies</subject><subject>Diagnostic Techniques, Endocrine</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Medical sciences</subject><subject>Non tumoral diseases</subject><subject>Obstetrics and Gynecology</subject><subject>Organ Size</subject><subject>Ovarian Cysts - blood</subject><subject>Ovarian Cysts - diagnosis</subject><subject>Ovarian Cysts - pathology</subject><subject>Ovary - pathology</subject><subject>Polycystic Ovary Syndrome - blood</subject><subject>Polycystic Ovary Syndrome - diagnosis</subject><subject>Polycystic Ovary Syndrome - pathology</subject><subject>Sensitivity and Specificity</subject><subject>Up-Regulation</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksFu1DAQhi0EotvCKyBfEPSQYCexk70glRVQpKIiLZwtrz1hvTj21nYW5R360DjahUpw4TK25O-f8cw_CGFKSkoof7MrewjJxZRjWRGyLCktCakeoQVljBeMs_oxWhBCWUGqrjpD5zHuCCGcttVTdJYlnFBaLdD9GsI4YOmSGUZrIRjp8NaHwTvAr68-X19iCwewEcsAGPJdJtDYOCy1txAVuIS_m5CBnyZt8d7bSU0xGYX9QQYDWeg0Tlv45ykXipPTwQ-50pfV7fryGXrSSxvh-em8QN8-vP-6ui5ubj9-Wl3dFKphXSpUq1S3YR0DrnNsqp73QFnVsZ7rpQLKoWug7ttmyWrWb7ikTHZtw3pdb6hu6gv06ph3H_zdCDGJweROrJUO_BhFFuap1XQmuyOpgo8xQC_2wQwyTIISMVshduLBCjFbISgV2YosfXEqMm4G0H-Ev2efgZcnQEYlbR-kUyY-cDXp2txc5t4duewCHAwEEZUBp0CbACoJ7c3__ObtX0mUNc7kuj9ggrjzY3B55IKKWAki1vPqzJtDlqRedrytfwE-asPL</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Hart, Roger, M.D</creator><creator>Doherty, Dorota A., Ph.D</creator><creator>Norman, Robert J., M.D</creator><creator>Franks, Stephen, F. 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| ispartof | Fertility and sterility, 2010-08, Vol.94 (3), p.1118-1121 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Adolescent Anti-Mullerian Hormone - blood Biological and medical sciences Biomarkers - blood Body Mass Index Cohort Studies Diagnostic Techniques, Endocrine Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Internal Medicine Medical sciences Non tumoral diseases Obstetrics and Gynecology Organ Size Ovarian Cysts - blood Ovarian Cysts - diagnosis Ovarian Cysts - pathology Ovary - pathology Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - diagnosis Polycystic Ovary Syndrome - pathology Sensitivity and Specificity Up-Regulation |
| title | Serum antimullerian hormone (AMH) levels are elevated in adolescent girls with polycystic ovaries and the polycystic ovarian syndrome (PCOS) |
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