DNA−Poly(diallyldimethylammonium chloride) Complexation and Transfection Efficiency

The present work assesses the influence of the cationic charge density (CD) and the cationic valence of poly(diallyldimethylammonium chloride) (pDADMAC) on the DNA compaction and subsequent transfection. Four homopolymers (CD = 1, with different valences) and one copolymer, poly(acrylamide-co-dially...

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Veröffentlicht in:	The journal of physical chemistry. B 2010-07, Vol.114 (29), p.9356-9366
Hauptverfasser:	Alatorre-Meda, Manuel, Taboada, Pablo, Krajewska, Barbara, Willemeit, Markus, Deml, Alexander, Klösel, Roland, Rodríguez, Julio R
Format:	Artikel
Sprache:	eng
Schlagworte:	B: Macromolecules, Soft Matter beta-Galactosidase - genetics beta-Galactosidase - metabolism Calorimetry DNA - chemistry Luciferases - genetics Luciferases - metabolism Microscopy, Atomic Force Polyethylenes - chemistry Quaternary Ammonium Compounds - chemistry Thermodynamics Transfection
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