Direct challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance

Direct bronchoprovocation challenges (eg, methacholine), which act directly on a specific airway smooth muscle receptor, are the most commonly performed challenge tests. Cut points have been arbitrarily selected to give high sensitivity and negative predictive values. In subjects with clinically cur...

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Veröffentlicht in:	Chest 2010-08, Vol.138 (2 Suppl), p.18S-24S
1. Verfasser:	Cockcroft, Donald W
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Asthma - diagnosis Asthma - physiopathology Bronchial Hyperreactivity - physiopathology Bronchial Provocation Tests - methods Bronchoconstriction - physiology Bronchoconstrictor Agents - administration & dosage Forced Expiratory Volume - physiology Humans Methacholine Chloride - administration & dosage Predictive Value of Tests Severity of Illness Index
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