Investigation of the developmental toxicity of cocaine in in vitro cultured chick embryos: Correlation of effects with intra-embryonic drug levels

The effects of cocaine and its primary metabolites, benzoylecgonine and ecgonine, on early embryogenesis were investigated in in vitro cultured chick embryos, and levels of cocaine and benzoylecgonine were measured in the embryo and in the culture medium. Neurulation was the only developmental proce...

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Veröffentlicht in:Toxicology in vitro 1991, Vol.5 (4), p.285-293
Hauptverfasser: Burin, G.J., Al-Ghaith, L.K., Anitole, K.G., Barber, M.K., Brown, K.M.
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Sprache:eng
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