From phenotype to gene: Detecting disease-specific gene functional modules via a text-based human disease phenotype network construction

Currently, some efforts have been devoted to the text analysis of disease phenotype data, and their results indicated that similar disease phenotypes arise from functionally related genes. These related genes work together, as a functional module, to perform a desired cellular function. We construct...

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Veröffentlicht in:	FEBS letters 2010-08, Vol.584 (16), p.3635-3643
Hauptverfasser:	Zhang, Shi-Hua, Wu, Chao, Li, Xia, Chen, Xi, Jiang, Wei, Gong, Bin-Sheng, Li, Jiang, Yan, Yu-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Cluster Analysis Computational Biology Databases, Genetic Disease - genetics Disease phenotype Gene functional module Gene Regulatory Networks Genetic origin Humans Phenotype Phenotype network Text mining
Online-Zugang:	Volltext
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