Direct evidence that an arene oxide is a metabolic intermediate of 2,2′,5,5′-tetrachlorobiphenyl

Radiolabeled arene oxide was recovered from incubations containing [ 3H]-2,2′,5,5′-tetrachlorobiphenyl ( 3H-TCB), unlabeled 2,2′,5,5′-tetrachlorobiphenyl-3,4-oxide (TCBAO), 3,3,3-trichloropropene-1,2-oxide (TCPO), NADPH, and liver microsomes from phenobarbital-induced rats. No labeled arene oxide wa...

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Veröffentlicht in:	Biochemical and biophysical research communications 1979-11, Vol.91 (2), p.475-483
Hauptverfasser:	Thomas Forgue, S., Preston, Bradley D., Hargraves, Walter A., Reich, Ieva L., Allen, James R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Epoxy Compounds - metabolism Ethers, Cyclic - metabolism Male Microsomes, Liver - drug effects Microsomes, Liver - metabolism NADP Phenobarbital - pharmacology Polychlorinated Biphenyls - metabolism Rats Tritium
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