Differential expression of NF-kappaB target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism

Mucosa-associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the nuclear factor (NF)-kappaB pathway. Gastric MALT lymphomas harboring such translocations usually do not respond...

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Veröffentlicht in:	Leukemia 2010-08, Vol.24 (8), p.1487-1497
Hauptverfasser:	Hamoudi, R A, Appert, A, Ye, H, Ruskone-Fourmestraux, A, Streubel, B, Chott, A, Raderer, M, Gong, L, Wlodarska, I, De Wolf-Peeters, C, MacLennan, K A, de Leval, L, Isaacson, P G, Du, M-Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics B-Cell CLL-Lymphoma 10 Protein Gene Expression Profiling Humans Immunohistochemistry Lymphoma, B-Cell, Marginal Zone - genetics Lymphoma, B-Cell, Marginal Zone - metabolism NF-kappa B - metabolism Oligonucleotide Array Sequence Analysis Oncogene Proteins, Fusion - genetics Reverse Transcriptase Polymerase Chain Reaction Toll-Like Receptor 6 - genetics Translocation, Genetic
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