Synergistic action of oncolytic herpes simplex virus and radiotherapy in pancreatic cancer cell lines

Background: Despite much research in chemotherapy and radiotherapy, pancreatic adenocarcinoma remains a fatal disease, highly resistant to all treatment modalities. Recent developments in the field of herpes simplex virus (HSV) engineering have allowed the generation of a number of promising virus v...

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Veröffentlicht in:	British journal of surgery 2010-09, Vol.97 (9), p.1385-1394
Hauptverfasser:	Dai, M.-H., Zamarin, D., Gao, S. P., Chou, T.-C., Gonzalez, L., Lin, S.-F., Fong, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Adenocarcinoma - radiotherapy Adenocarcinoma - therapy Apoptosis Biological and medical sciences Cell Survival Coloring Agents Combined Modality Therapy DNA Nucleotidylexotransferase - metabolism Gamma Rays - therapeutic use Gastroenterology. Liver. Pancreas. Abdomen General aspects Genetic Therapy - methods Genetic Vectors Herpesvirus 1, Human Humans In Situ Nick-End Labeling Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Pancreatic Neoplasms - pathology Pancreatic Neoplasms - radiotherapy Pancreatic Neoplasms - therapy Propidium Simplexvirus Tumor Cells, Cultured Tumors Virus Replication - radiation effects
Online-Zugang:	Volltext
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