oleate-stimulated, phosphatidylinositol 4,5-bisphosphate-independent phospholipase D in Schizosaccharomyces pombe

Phospholipase D1 (PLD1) is an important enzyme involved in lipid-mediated signal transduction and membrane dynamics in eukaryotes. PLD1 preferentially hydrolyzes phosphatidylcholine to phosphatidic acid. This potent second messenger is involved in cytoskeletal reorganization, secretion, and membrane...

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Veröffentlicht in:	FEMS yeast research 2010-09, Vol.10 (6), p.717-726
Hauptverfasser:	Harkins, April L, Yuan, Guangzhi, London, Steven D, Dolan, Joseph W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Candida albicans Candida albicans - enzymology Candida albicans - metabolism Cloning, Molecular Cytoskeleton DNA, Fungal - chemistry DNA, Fungal - genetics Enzymes Eukaryota Gene Library Homology Lecithin Membrane trafficking Molecular Sequence Data Morphogenesis oleate oleic acid Oleic Acid - metabolism Phosphatidic acid Phosphatidylcholine Phosphatidylcholines - metabolism Phosphatidylinositol 4,5-diphosphate Phosphatidylinositol 4,5-Diphosphate - genetics Phosphatidylinositol 4,5-Diphosphate - metabolism Phospholipase D Phospholipase D - metabolism Phospholipase D1 PIP PIP2 Recombination, Genetic Saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - metabolism Schizosaccharomyces - enzymology Schizosaccharomyces - genetics Schizosaccharomyces - metabolism Schizosaccharomyces pombe Sequence Alignment Sequence Analysis, DNA Signal transduction Spores, Fungal - growth & development Sporulation Yeast
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