Effect of combined administration of transforming growth factor-b1 and insulin-like growth factor I on the mechanical properties of a patellar tendon defect model in rabbits

The aim of this study was to test the hypothesis that combined administration of TGF-b1 and IGF-I in a patellar tendon defect model could enhance the mechanical properties of the healed tendon. Twenty four New Zealand white rabbits were used for this purpose. In each animal, the right knee was used...

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Veröffentlicht in:	Acta orthopaedica belgica 2010-06, Vol.76 (3), p.380-386
Hauptverfasser:	Lyras, Dimitrios N, Kazakos, Konstantinos, Verettas, Dionysios, Chronopoulos, Efstathios, Folaranmi, Semiu, Agrogiannis, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomechanical Phenomena Disease Models, Animal Insulin-Like Growth Factor I - administration & dosage Male Patellar Ligament - drug effects Patellar Ligament - injuries Rabbits Recombinant Proteins - administration & dosage Regeneration - physiology Transforming Growth Factor beta1 - administration & dosage Wound Healing - drug effects Wound Healing - physiology
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