Precision-cut hamster liver slices as an ex vivo model to study amoebic liver abscess

Entamoeba histolytica is the etiological agent of amoebiasis, the second cause of global morbidity and mortality due to parasitic diseases in humans. In approximately 1% of the cases, amoebas penetrate the intestinal mucosa and spread to other organs, producing extra-intestinal lesions, among which...

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Veröffentlicht in:	Experimental parasitology 2010-10, Vol.126 (2), p.117-125
Hauptverfasser:	Carranza-Rosales, Pilar, Santiago-Mauricio, María Guadalupe, Guzmán-Delgado, Nancy Elena, Vargas-Villarreal, Javier, Lozano-Garza, Gerardo, Ventura-Juárez, Javier, Balderas-Rentería, Isaías, Morán-Martínez, Javier, Gandolfi, A. Jay
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - analysis Actins - genetics Amoebic liver abscess Animals Biological and medical sciences Cricetinae Cysteine Proteases - analysis Cysteine Proteases - genetics Disease Models, Animal DNA, Complementary - analysis Entamoeba histolytica Entamoeba histolytica - genetics Entamoeba histolytica - pathogenicity Ex vivo model Fundamental and applied biological sciences. Psychology Hamster Ion Channels - analysis Ion Channels - genetics Life cycle. Host-agent relationship. Pathogenesis Liver - parasitology Liver Abscess, Amebic - parasitology Liver Abscess, Amebic - pathology Liver slices Male Mesocricetus Polymerase Chain Reaction Protozoa Protozoan Proteins - analysis Protozoan Proteins - genetics RNA, Protozoan - genetics RNA, Protozoan - isolation & purification Tissue Culture Techniques Virulence Virulence Factors - analysis Virulence Factors - genetics
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