Increased Food Intake and Energy Expenditure Following Administration of Olanzapine to Healthy Men

Atypical antipsychotic medications like olanzapine (OLZ) induce weight gain and increase the risk of diabetes in patients with schizophrenia. The goal of this study was to assess potential mechanisms of OLZ‐induced weight gain and accompanying metabolic effects. Healthy, lean, male volunteers receiv...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2010-08, Vol.18 (8), p.1646-1651
Hauptverfasser:	Fountaine, Robert J., Taylor, Ann E., Mancuso, James P., Greenway, Frank L., Byerley, Lauri O., Smith, Steven R., Most, Marlene M., Fryburg, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antipsychotic Agents - adverse effects Basal Metabolism - drug effects Benzodiazepines - adverse effects Biomarkers - blood Double-Blind Method Energy Intake - drug effects Exercise Humans Insulin Resistance Leptin - blood Male Middle Aged Plasminogen Activator Inhibitor 1 - blood Reference Values Triglycerides - blood Tumor Necrosis Factor-alpha - blood Weight Gain - drug effects Young Adult
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