$Central nervous system activity of the proanthocyanidin-rich fraction obtained from Croton celtidifolius in rats$

Central nervous system activity of the proanthocyanidin-rich fraction obtained from Croton celtidifolius in rats

Objectives The aim of the present study was to evaluate the possible neurobehavioural effects in rats of the proanthocyanidin‐rich fraction (PRF) isolated from the bark of Croton celtidifolius (Euphorbiaceae). Methods Adult Wistar rats were treated with the PRF (0.3–30 mg/kg) and evaluated in diff...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2010-08, Vol.62 (8), p.1061-1068
Hauptverfasser:	Moreira, Eduardo L.G., Rial, Daniel, Duarte, Filipe S., De Carvalho, Cristiane Ribeiro, Horst, Heros, Pizzolatti, Moacir G., Prediger, Rui D.S., Ribeiro-do-Valle, Rosa Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Inhalation - pharmacology Animals Anti-Anxiety Agents - pharmacology Anticonvulsants - pharmacology Antipsychotic Agents - pharmacology Apomorphine - pharmacology Behavior, Animal - drug effects behaviour catechin central actions Central Nervous System Agents - administration & dosage Central Nervous System Agents - isolation & purification Central Nervous System Agents - pharmacology Consciousness - drug effects Croton - chemistry Croton celtidifolius Disease Models, Animal Dose-Response Relationship, Drug Ether - pharmacology Hypnotics and Sedatives - pharmacology Injections, Intraperitoneal Male Motor Activity - drug effects Pentylenetetrazole Plant Bark Plant Extracts - administration & dosage Plant Extracts - pharmacology proanthocyanidin Proanthocyanidins - administration & dosage Proanthocyanidins - isolation & purification Proanthocyanidins - pharmacology Rats Rats, Wistar Seizures - chemically induced Seizures - prevention & control Stereotyped Behavior - drug effects
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