Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer

Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology ca...

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Veröffentlicht in:RADIOISOTOPES 1979/06/15, Vol.28(6), pp.367-370
Hauptverfasser: OSHIUMI, Yoshihiko, YAGI, Hiroo, NISHITANI, Hiromu, YAMAWAKI, Hitoshi, NAKAYAMA, Chikashi, KAMOI, Itsuma, MATSUURA, Keiichi, MOMOSE, Shunro
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container_end_page 370
container_issue 6
container_start_page 367
container_title RADIOISOTOPES
container_volume 28
creator OSHIUMI, Yoshihiko
YAGI, Hiroo
NISHITANI, Hiromu
YAMAWAKI, Hitoshi
NAKAYAMA, Chikashi
KAMOI, Itsuma
MATSUURA, Keiichi
MOMOSE, Shunro
description Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology cases (class I and II) . Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer.
doi_str_mv 10.3769/radioisotopes.28.6_367
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subjects Adult
Aged
bladder cancer
Carcinoembryonic Antigen - urine
Carcinoma, Transitional Cell - diagnosis
Carcinoma, Transitional Cell - urine
exfoliative cytology
Female
Humans
Male
Middle Aged
Urinary Bladder Neoplasms - diagnosis
Urinary Bladder Neoplasms - urine
urinary carcinoembryonic antigen
Urine - cytology
title Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer
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