Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer
Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology ca...
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Veröffentlicht in: | RADIOISOTOPES 1979/06/15, Vol.28(6), pp.367-370 |
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creator | OSHIUMI, Yoshihiko YAGI, Hiroo NISHITANI, Hiromu YAMAWAKI, Hitoshi NAKAYAMA, Chikashi KAMOI, Itsuma MATSUURA, Keiichi MOMOSE, Shunro |
description | Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology cases (class I and II) . Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer. |
doi_str_mv | 10.3769/radioisotopes.28.6_367 |
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There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology cases (class I and II) . Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. 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There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology cases (class I and II) . Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer.</description><subject>Adult</subject><subject>Aged</subject><subject>bladder cancer</subject><subject>Carcinoembryonic Antigen - urine</subject><subject>Carcinoma, Transitional Cell - diagnosis</subject><subject>Carcinoma, Transitional Cell - urine</subject><subject>exfoliative cytology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Urinary Bladder Neoplasms - diagnosis</subject><subject>Urinary Bladder Neoplasms - urine</subject><subject>urinary carcinoembryonic antigen</subject><subject>Urine - cytology</subject><issn>0033-8303</issn><issn>1884-4111</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE9P4zAQxS3EAoXlGyDkE7cU_4vjHCHqwkqgPRT2ak2cSTFKnWKnh_32pBuo1NNYer_3ZvwIueZsLgtd3kZofO9TP_QbTHNh5tpKXRyRGTdGZYpzfkxmjEmZGcnkGTlP6Z0xoXNWnJKTXHKRlzPyt-p88A46uvSr4NvxGRzSvqWv0QeI_2i1uKPPCGkbcY1hoJAo0KWLiMGHFX3BNOzw-w6aBiOtdv74k_xooUt4-TUvyOuvxUv1mD39efhd3T1lTipRZNAq0KyVLldlzTSvRYOgGoW1LPO80Wi00wVTjGtooYHaCMY4gFIlFshKeUFuptxN7D-24yl27ZPDroOA_TbZQhnDRJmPoJ5AF_uUIrZ2E_16_J_lzO76tAd9WmHs_z5H49XXhm29xmZvmwoc5edJfk8DrHAvQxy86_AwlZe5mJK_4_ece4NoMchPKvKRqQ</recordid><startdate>1979</startdate><enddate>1979</enddate><creator>OSHIUMI, Yoshihiko</creator><creator>YAGI, Hiroo</creator><creator>NISHITANI, Hiromu</creator><creator>YAMAWAKI, Hitoshi</creator><creator>NAKAYAMA, Chikashi</creator><creator>KAMOI, Itsuma</creator><creator>MATSUURA, Keiichi</creator><creator>MOMOSE, Shunro</creator><general>Japan Radioisotope Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1979</creationdate><title>Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer</title><author>OSHIUMI, Yoshihiko ; YAGI, Hiroo ; NISHITANI, Hiromu ; YAMAWAKI, Hitoshi ; NAKAYAMA, Chikashi ; KAMOI, Itsuma ; MATSUURA, Keiichi ; MOMOSE, Shunro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3427-af4a60f3c549b061b2dea4d4eb3955d6e86c6704016afadab82001aa449e7e093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Aged</topic><topic>bladder cancer</topic><topic>Carcinoembryonic Antigen - urine</topic><topic>Carcinoma, Transitional Cell - diagnosis</topic><topic>Carcinoma, Transitional Cell - urine</topic><topic>exfoliative cytology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Urinary Bladder Neoplasms - diagnosis</topic><topic>Urinary Bladder Neoplasms - urine</topic><topic>urinary carcinoembryonic antigen</topic><topic>Urine - cytology</topic><toplevel>online_resources</toplevel><creatorcontrib>OSHIUMI, Yoshihiko</creatorcontrib><creatorcontrib>YAGI, Hiroo</creatorcontrib><creatorcontrib>NISHITANI, Hiromu</creatorcontrib><creatorcontrib>YAMAWAKI, Hitoshi</creatorcontrib><creatorcontrib>NAKAYAMA, Chikashi</creatorcontrib><creatorcontrib>KAMOI, Itsuma</creatorcontrib><creatorcontrib>MATSUURA, Keiichi</creatorcontrib><creatorcontrib>MOMOSE, Shunro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>RADIOISOTOPES</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OSHIUMI, Yoshihiko</au><au>YAGI, Hiroo</au><au>NISHITANI, Hiromu</au><au>YAMAWAKI, Hitoshi</au><au>NAKAYAMA, Chikashi</au><au>KAMOI, Itsuma</au><au>MATSUURA, Keiichi</au><au>MOMOSE, Shunro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer</atitle><jtitle>RADIOISOTOPES</jtitle><addtitle>Radioisotopes</addtitle><date>1979</date><risdate>1979</risdate><volume>28</volume><issue>6</issue><spage>367</spage><epage>370</epage><pages>367-370</pages><issn>0033-8303</issn><eissn>1884-4111</eissn><abstract>Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V) . CEA measurements were positive in 8 of 11 negative cytology cases (class I and II) . Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer.</abstract><cop>Japan</cop><pub>Japan Radioisotope Association</pub><pmid>531259</pmid><doi>10.3769/radioisotopes.28.6_367</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged bladder cancer Carcinoembryonic Antigen - urine Carcinoma, Transitional Cell - diagnosis Carcinoma, Transitional Cell - urine exfoliative cytology Female Humans Male Middle Aged Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - urine urinary carcinoembryonic antigen Urine - cytology |
title | Clinical Significance of Urinary CEA Measurement as a Screening Test of Bladder Cancer |
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