Appearance of Bone Marrow Smears With Necrotic Tumor Cells

Appearance of Bone Marrow Smears With Necrotic Tumor Cells

Bone marrow smears of necrotic tumor cells stained with Romanowsky dyes frequently have a definite reddish color that contrasts so strikingly with the blue color of normal marrow that necrosis may be suspected from gross examination. The bone marrow cells appear “smudged” and are difficult to identi...

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Veröffentlicht in:Blood 1971-08, Vol.38 (2), p.229-231
Hauptverfasser: Brittin, Geoffrey M., Brecher, George
Format: Artikel
Sprache:eng
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Bone Marrow Examination
Humans
Leukemia - pathology
Methods
Necrosis - pathology
Staining and Labeling
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Brecher, George
description Bone marrow smears of necrotic tumor cells stained with Romanowsky dyes frequently have a definite reddish color that contrasts so strikingly with the blue color of normal marrow that necrosis may be suspected from gross examination. The bone marrow cells appear “smudged” and are difficult to identify on microscopic examination. Commonly, only a small amount of material is obtainable by ordinary needle aspiration of bone marrow containing necrotic tumor, and all of it is used to make smears. It is therefore important to recognize that bone marrow smears with a reddish gross appearance and in which the cells appear distorted and are difficult to identify may represent necrotic tumor and not an artifact produced by poor techniques.
doi_str_mv 10.1182/blood.V38.2.229.229
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Bone Marrow Examination
Humans
Leukemia - pathology
Methods
Necrosis - pathology
Staining and Labeling
title Appearance of Bone Marrow Smears With Necrotic Tumor Cells
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