Prevention of the development of spontaneous hypertension in rats by captopril (SQ 14,225)

Indirect systolic blood pressure (SBP) was monitored in male, spontaneously hypertensive rats (SHR) maintained on water for 16 weeks (group A) or on captopril therapy (100 mg/kg/day in drinking water) for 4 (group B), 8 (group C), 12 (group D), 16 (group E) weeks. Weanling SHR of group A developed t...

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Veröffentlicht in:	European journal of pharmacology 1979-12, Vol.60 (2), p.131-137
Hauptverfasser:	Ferrone, Ronald A., Antonaccio, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - drug effects Body Weight - drug effects Captopril Captopril - therapeutic use Development of hypertension Drinking Drinking Behavior - drug effects Heart Rate - drug effects Hypertension - prevention & control Male Proline - analogs & derivatives Rats SHR Time Factors
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