Melatonin excretion, body temperature and subjective arousal during 64 hours of sleep deprivation

(1) Evidence has been presented, based on measurement of melatonin by radioimmunoassay in 12 healthy males, that the urinary excretion of melatonin follows a circadian pattern in humans during sleep deprivation when the subjects are exposed to light. (2) Melatonin excretion increased with increased...

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Veröffentlicht in:Psychoneuroendocrinology 1979-07, Vol.4 (3), p.219-225
Hauptverfasser: Åkerstedt, Torbjörn, Fröberg, Jan E., Friberg, Ylva, Wetterberg, Lennart
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container_issue 3
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container_title Psychoneuroendocrinology
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creator Åkerstedt, Torbjörn
Fröberg, Jan E.
Friberg, Ylva
Wetterberg, Lennart
description (1) Evidence has been presented, based on measurement of melatonin by radioimmunoassay in 12 healthy males, that the urinary excretion of melatonin follows a circadian pattern in humans during sleep deprivation when the subjects are exposed to light. (2) Melatonin excretion increased with increased sleep deprivation. (3) Melatonin excretion during recovery sleep did not differ from that during base line sleep. (4) Melatonin excretion did not react to psychosocial stress at trough times (as adrenaline did). (5) Self-rated fatigue and body temperature exhibited a circadian variation. (6) Peak fatigue and trough body temperature coincided temporally with the peak of melatonin excretion.
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source Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects Adult
Arousal - physiology
Body Temperature
circadian rhythms
Fatigue - urine
Humans
Male
melatonin
Melatonin - urine
Sleep Deprivation
subjective arousal
title Melatonin excretion, body temperature and subjective arousal during 64 hours of sleep deprivation
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