Improved remission induction rate with D-ZAPO but unimproved remission duration with addition of immunotherapy to chemotherapy in previously untreated children with ANLL

In 163 children with acute nonlymphocytic leukemia (ANLL), a D‐ZAPO induction program consisting of daunomycin, 5‐azacytidine, cytosine arabinoside, prednisone, and vincristine resulted in a remission rate of 71.8%. Immunologic therapy was employed during maintenance with the aim of prolonging remis...

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Veröffentlicht in:	Medical and pediatric oncology 1979, Vol.7 (2), p.127-139
Hauptverfasser:	Baehner, Robert L., Bernstein, Irwin D., Sather, Harland, Higgins, Gussie, McCreadie, Samuel, Chard, Ronald L., Hammond, Denman
Format:	Artikel
Sprache:	eng
Schlagworte:	acute nonlymphocytic leukemia Adolescent Adult Antigens, Neoplasm - administration & dosage Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects BCG Vaccine - administration & dosage Bone Marrow - drug effects Central Nervous System Diseases - therapy chemotherapy Child Child, Preschool Drug Therapy, Combination Female Humans Immunotherapy Leukemia - therapy Leukemia, Myeloid, Acute - immunology Leukocyte Count Male prognostic factors Remission, Spontaneous Skin Tests
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