Human dihydropteridine reductase a method for the measurement of activity in cultured cells, and its application to malignant hyperphenylalaninemia

1. 1. The kinetic, assay and culture variables involved in the determination of dihydropteridine reductase activity in human cultured cells have been investi gated, and a modified assay is described which allows for accurate determination of activity. Unlike previously used assays, this assay utiliz...

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Veröffentlicht in:	Clinica chimica acta 1979-07, Vol.95 (1), p.47-59
Hauptverfasser:	Firgaria, Frank A., Cotton, Richard G.H., Danks, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic Fluid - enzymology Animals Cells, Cultured Dihydropteridine Reductase - analysis Dihydropteridine Reductase - metabolism Female Humans Hydrogen-Ion Concentration Liver - enzymology Lymphocytes - enzymology Male Methods NADH, NADPH Oxidoreductases - analysis Phenylalanine - blood Phenylketonurias - enzymology Pregnancy Rats Sheep Temperature
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