Leukemia in a black child with Bloom's syndrome. Somatic recombination as a possible mechanism for neoplasia

A 5 1/2‐year‐old black child with Bloom's syndrome developed acute lymphocytic leukemia (ALL). Bloom's syndrome is associated with chromosomal aberrations, and affected individuals have an increased incidence of leukemia and solid tumors. The skin on our patient had adjacent areas of decre...

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Veröffentlicht in:	Cancer 1979-10, Vol.44 (4), p.1507-1510
Hauptverfasser:	Festa, Robert S., Meadows, Anna T., Boshes, Roger A.
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group Child, Preschool Chromosome Aberrations Dwarfism - complications Dwarfism - genetics Humans Leukemia, Lymphoid - complications Leukemia, Lymphoid - genetics Male Mutation Pigmentation Disorders - complications Pigmentation Disorders - genetics Recombination, Genetic Sister Chromatid Exchange Syndrome
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