Static pion beam treatment planning of deep seated tumors using computerized tomographic scans
Static negative pion beam treatment of deep seated tumors is in progress at LAMPF. The influence of the physical principles of pions on treatment planning, e.g., an enhanced peak dose, multiple scattering, variations of beam quality, pin beam emittance, and a fixed vertical beam, are discussed. Comp...
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| Veröffentlicht in: | Int. J. Radiat. Oncol., Biol. Phys.; (United States) Biol. Phys.; (United States), 1979-06, Vol.5 (6), p.875-886 |
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| container_title | Int. J. Radiat. Oncol., Biol. Phys.; (United States) |
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| creator | Hogstrom, Kenneth R. Smith, Alfred R. Simon, Steve L. Somers, John W. Lane, Richard G. Rosen, Isaac I. Kelsey, Charles A. von Essen, Carl F. Kligerman, Morton M. Berardo, Peter A. Zink, Sandra M. |
| description | Static negative pion beam treatment of deep seated tumors is in progress at LAMPF. The influence of the physical principles of pions on treatment planning, e.g., an enhanced peak dose, multiple scattering, variations of beam quality, pin beam emittance, and a fixed vertical beam, are discussed. Computerized tomographic (CT) scan data have proven invaluable in providing quantitative information on inhomogeneities within the anatomy. The methods of designing collimation and compensating bolus for tailoring the pion beam to individual patient ports are described. An interim method, using dosimetry measurements in a water phantom and CT scan data to construct patient isodose distribution is outlined. Typical treatment plans for patients with abdominal and head and neck cancers are presented. The method of X-ray simulation in verifying localization of CT-defined tumor volumes is demonstrated for the head and neck. |
| doi_str_mv | 10.1016/0360-3016(79)90072-5 |
| format | Article |
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The influence of the physical principles of pions on treatment planning, e.g., an enhanced peak dose, multiple scattering, variations of beam quality, pin beam emittance, and a fixed vertical beam, are discussed. Computerized tomographic (CT) scan data have proven invaluable in providing quantitative information on inhomogeneities within the anatomy. The methods of designing collimation and compensating bolus for tailoring the pion beam to individual patient ports are described. An interim method, using dosimetry measurements in a water phantom and CT scan data to construct patient isodose distribution is outlined. Typical treatment plans for patients with abdominal and head and neck cancers are presented. The method of X-ray simulation in verifying localization of CT-defined tumor volumes is demonstrated for the head and neck.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/0360-3016(79)90072-5</identifier><identifier>PMID: 500416</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>550602 - Medicine- External Radiation in Diagnostics- (1980-) ; 550603 - Medicine- External Radiation in Therapy- (1980-) ; 560151 - Radiation Effects on Animals- Man ; ABDOMEN ; Adenocarcinoma - radiotherapy ; BODY ; BODY AREAS ; BOSONS ; CAT SCANNING ; COLLIMATORS ; COMPARATIVE EVALUATIONS ; Computerized tomography scans ; DATA ; DATA FORMS ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DISEASES ; DOSE RATES ; ELEMENTARY PARTICLES ; EXPERIMENTAL DATA ; EXTERNAL IRRADIATION ; HADRONS ; HEAD ; Humans ; Hypopharynx ; INFORMATION ; Inhomogeneity corrections ; IRRADIATION ; ISOLATED VALUES ; MEDICINE ; MESONS ; NECK ; NEOPLASMS ; Neoplasms - radiotherapy ; NUCLEAR MEDICINE ; NUMERICAL DATA ; Pancreatic Neoplasms - radiotherapy ; PARTIAL BODY IRRADIATION ; PATIENTS ; Pharyngeal Neoplasms - radiotherapy ; PHOTON TRANSMISSION SCANNING ; Pion dosimetry ; Pion radiotherapy ; PIONS ; PIONS MINUS ; PLANNING ; PSEUDOSCALAR MESONS ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Radiotherapy Dosage ; THERAPY ; TOMOGRAPHY ; Tomography, X-Ray Computed ; Treatment planning</subject><ispartof>Int. J. Radiat. Oncol., Biol. 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J. Radiat. Oncol., Biol. Phys.; (United States)</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Static negative pion beam treatment of deep seated tumors is in progress at LAMPF. The influence of the physical principles of pions on treatment planning, e.g., an enhanced peak dose, multiple scattering, variations of beam quality, pin beam emittance, and a fixed vertical beam, are discussed. Computerized tomographic (CT) scan data have proven invaluable in providing quantitative information on inhomogeneities within the anatomy. The methods of designing collimation and compensating bolus for tailoring the pion beam to individual patient ports are described. An interim method, using dosimetry measurements in a water phantom and CT scan data to construct patient isodose distribution is outlined. Typical treatment plans for patients with abdominal and head and neck cancers are presented. The method of X-ray simulation in verifying localization of CT-defined tumor volumes is demonstrated for the head and neck.</description><subject>550602 - Medicine- External Radiation in Diagnostics- (1980-)</subject><subject>550603 - Medicine- External Radiation in Therapy- (1980-)</subject><subject>560151 - Radiation Effects on Animals- Man</subject><subject>ABDOMEN</subject><subject>Adenocarcinoma - radiotherapy</subject><subject>BODY</subject><subject>BODY AREAS</subject><subject>BOSONS</subject><subject>CAT SCANNING</subject><subject>COLLIMATORS</subject><subject>COMPARATIVE EVALUATIONS</subject><subject>Computerized tomography scans</subject><subject>DATA</subject><subject>DATA FORMS</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>DOSE RATES</subject><subject>ELEMENTARY PARTICLES</subject><subject>EXPERIMENTAL DATA</subject><subject>EXTERNAL IRRADIATION</subject><subject>HADRONS</subject><subject>HEAD</subject><subject>Humans</subject><subject>Hypopharynx</subject><subject>INFORMATION</subject><subject>Inhomogeneity corrections</subject><subject>IRRADIATION</subject><subject>ISOLATED VALUES</subject><subject>MEDICINE</subject><subject>MESONS</subject><subject>NECK</subject><subject>NEOPLASMS</subject><subject>Neoplasms - radiotherapy</subject><subject>NUCLEAR MEDICINE</subject><subject>NUMERICAL DATA</subject><subject>Pancreatic Neoplasms - radiotherapy</subject><subject>PARTIAL BODY IRRADIATION</subject><subject>PATIENTS</subject><subject>Pharyngeal Neoplasms - radiotherapy</subject><subject>PHOTON TRANSMISSION SCANNING</subject><subject>Pion dosimetry</subject><subject>Pion radiotherapy</subject><subject>PIONS</subject><subject>PIONS MINUS</subject><subject>PLANNING</subject><subject>PSEUDOSCALAR MESONS</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy Dosage</subject><subject>THERAPY</subject><subject>TOMOGRAPHY</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment planning</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFuFSEUhompttdb36AL4sLUxVgY4DJsTEzTqkkTF9bEVQkDZ25p7sAIjIk-fRmn6dIVJN9__pzzIXRGyQdK6O6CsB1pWP2dS_VeESLbRrxAG9pJ1TAhfh6hzXPkBL3O-YEQQqnkx-iVIITT3QbdfS-meIsnHwPuwYy4JDBlhFDwdDAh-LDHccAOYMK5EnC4zGNMGc95YTaO01wg-b8LiWPcJzPd18ZsTcin6OVgDhnePL1b9OP66vbyS3Pz7fPXy083jWUdK82g2l4548jQCuOsBT60TnWVGdWBEz1vids5qTqrGGHOcE5hoEb1hg7WWbZFb9femIvX2foC9t7GEMAWLaQSRLAaereGphR_zZCLHn22cKhnQpyzllx2lFJeg3wN2hRzTjDoKfnRpD-aEr2o14tXvXjVUul_6rWoY2dP_XM_gnseWl1X_HHFUEX89pCWPSFYcD4ta7ro_9__CAz7lJs</recordid><startdate>197906</startdate><enddate>197906</enddate><creator>Hogstrom, Kenneth R.</creator><creator>Smith, Alfred R.</creator><creator>Simon, Steve L.</creator><creator>Somers, John W.</creator><creator>Lane, Richard G.</creator><creator>Rosen, Isaac I.</creator><creator>Kelsey, Charles A.</creator><creator>von Essen, Carl F.</creator><creator>Kligerman, Morton M.</creator><creator>Berardo, Peter A.</creator><creator>Zink, Sandra M.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>197906</creationdate><title>Static pion beam treatment planning of deep seated tumors using computerized tomographic scans</title><author>Hogstrom, Kenneth R. ; Smith, Alfred R. ; Simon, Steve L. ; Somers, John W. ; Lane, Richard G. ; Rosen, Isaac I. ; Kelsey, Charles A. ; von Essen, Carl F. ; Kligerman, Morton M. ; Berardo, Peter A. ; Zink, Sandra M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c383t-f92b9dad0f25adcce4f2d98383a98ed5b420d6d798c9303da441ef1a9ba1fcdc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>550602 - Medicine- External Radiation in Diagnostics- (1980-)</topic><topic>550603 - Medicine- External Radiation in Therapy- (1980-)</topic><topic>560151 - Radiation Effects on Animals- Man</topic><topic>ABDOMEN</topic><topic>Adenocarcinoma - radiotherapy</topic><topic>BODY</topic><topic>BODY AREAS</topic><topic>BOSONS</topic><topic>CAT SCANNING</topic><topic>COLLIMATORS</topic><topic>COMPARATIVE EVALUATIONS</topic><topic>Computerized tomography scans</topic><topic>DATA</topic><topic>DATA FORMS</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>DOSE RATES</topic><topic>ELEMENTARY PARTICLES</topic><topic>EXPERIMENTAL DATA</topic><topic>EXTERNAL IRRADIATION</topic><topic>HADRONS</topic><topic>HEAD</topic><topic>Humans</topic><topic>Hypopharynx</topic><topic>INFORMATION</topic><topic>Inhomogeneity corrections</topic><topic>IRRADIATION</topic><topic>ISOLATED VALUES</topic><topic>MEDICINE</topic><topic>MESONS</topic><topic>NECK</topic><topic>NEOPLASMS</topic><topic>Neoplasms - radiotherapy</topic><topic>NUCLEAR MEDICINE</topic><topic>NUMERICAL DATA</topic><topic>Pancreatic Neoplasms - radiotherapy</topic><topic>PARTIAL BODY IRRADIATION</topic><topic>PATIENTS</topic><topic>Pharyngeal Neoplasms - radiotherapy</topic><topic>PHOTON TRANSMISSION SCANNING</topic><topic>Pion dosimetry</topic><topic>Pion radiotherapy</topic><topic>PIONS</topic><topic>PIONS MINUS</topic><topic>PLANNING</topic><topic>PSEUDOSCALAR MESONS</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy Dosage</topic><topic>THERAPY</topic><topic>TOMOGRAPHY</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment planning</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hogstrom, Kenneth R.</creatorcontrib><creatorcontrib>Smith, Alfred R.</creatorcontrib><creatorcontrib>Simon, Steve L.</creatorcontrib><creatorcontrib>Somers, John W.</creatorcontrib><creatorcontrib>Lane, Richard G.</creatorcontrib><creatorcontrib>Rosen, Isaac I.</creatorcontrib><creatorcontrib>Kelsey, Charles A.</creatorcontrib><creatorcontrib>von Essen, Carl F.</creatorcontrib><creatorcontrib>Kligerman, Morton M.</creatorcontrib><creatorcontrib>Berardo, Peter A.</creatorcontrib><creatorcontrib>Zink, Sandra M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Int. J. Radiat. Oncol., Biol. Phys.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hogstrom, Kenneth R.</au><au>Smith, Alfred R.</au><au>Simon, Steve L.</au><au>Somers, John W.</au><au>Lane, Richard G.</au><au>Rosen, Isaac I.</au><au>Kelsey, Charles A.</au><au>von Essen, Carl F.</au><au>Kligerman, Morton M.</au><au>Berardo, Peter A.</au><au>Zink, Sandra M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Static pion beam treatment planning of deep seated tumors using computerized tomographic scans</atitle><jtitle>Int. J. Radiat. Oncol., Biol. Phys.; (United States)</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>1979-06</date><risdate>1979</risdate><volume>5</volume><issue>6</issue><spage>875</spage><epage>886</epage><pages>875-886</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><abstract>Static negative pion beam treatment of deep seated tumors is in progress at LAMPF. The influence of the physical principles of pions on treatment planning, e.g., an enhanced peak dose, multiple scattering, variations of beam quality, pin beam emittance, and a fixed vertical beam, are discussed. Computerized tomographic (CT) scan data have proven invaluable in providing quantitative information on inhomogeneities within the anatomy. The methods of designing collimation and compensating bolus for tailoring the pion beam to individual patient ports are described. An interim method, using dosimetry measurements in a water phantom and CT scan data to construct patient isodose distribution is outlined. Typical treatment plans for patients with abdominal and head and neck cancers are presented. The method of X-ray simulation in verifying localization of CT-defined tumor volumes is demonstrated for the head and neck.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>500416</pmid><doi>10.1016/0360-3016(79)90072-5</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0360-3016 |
| ispartof | Int. J. Radiat. Oncol., Biol. Phys.; (United States), 1979-06, Vol.5 (6), p.875-886 |
| issn | 0360-3016 1879-355X |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | 550602 - Medicine- External Radiation in Diagnostics- (1980-) 550603 - Medicine- External Radiation in Therapy- (1980-) 560151 - Radiation Effects on Animals- Man ABDOMEN Adenocarcinoma - radiotherapy BODY BODY AREAS BOSONS CAT SCANNING COLLIMATORS COMPARATIVE EVALUATIONS Computerized tomography scans DATA DATA FORMS DIAGNOSIS DIAGNOSTIC TECHNIQUES DISEASES DOSE RATES ELEMENTARY PARTICLES EXPERIMENTAL DATA EXTERNAL IRRADIATION HADRONS HEAD Humans Hypopharynx INFORMATION Inhomogeneity corrections IRRADIATION ISOLATED VALUES MEDICINE MESONS NECK NEOPLASMS Neoplasms - radiotherapy NUCLEAR MEDICINE NUMERICAL DATA Pancreatic Neoplasms - radiotherapy PARTIAL BODY IRRADIATION PATIENTS Pharyngeal Neoplasms - radiotherapy PHOTON TRANSMISSION SCANNING Pion dosimetry Pion radiotherapy PIONS PIONS MINUS PLANNING PSEUDOSCALAR MESONS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage THERAPY TOMOGRAPHY Tomography, X-Ray Computed Treatment planning |
| title | Static pion beam treatment planning of deep seated tumors using computerized tomographic scans |
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