The effects of actinomycin D and cordycepin on neurite formation and acetylcholinesterase activity in mouse neuroblastoma cells

Actinomycin D (actD) (0.003–0.10 μg/ml) and cordycepin (3–30 μg/ml) were used to examine the requirement of de novo RNA synthesis in the pH 6.6-induced expression of neurites and acetylcholinesterase activity in C-1300 mouse neuroblastoma cells. ActD at 0.03 and 0.10 μg/ml caused a pronounced stimul...

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Veröffentlicht in:	Experimental cell research 1979-10, Vol.123 (2), p.301-309
Hauptverfasser:	Bear, Mark P., Schneider, F.Howard
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - metabolism Animals Cell Differentiation - drug effects Cell Line Cell Survival - drug effects Dactinomycin - pharmacology Deoxyadenosines - pharmacology Dose-Response Relationship, Drug Mice Neuroblastoma - ultrastructure Neurons - drug effects Neurons - enzymology Neurons - ultrastructure RNA - biosynthesis
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