Similarity of Hematologic Effect of Pyridoxine Deficiency, Cortisone, and Myeloid Metaplasia Factor of Human Urine.

Similarity of Hematologic Effect of Pyridoxine Deficiency, Cortisone, and Myeloid Metaplasia Factor of Human Urine.

Summary Similar hematologic and histologic changes occurred in mice made pyridoxine deficient, in mice treated with cortisone, and in mice treated with a myeloid metaplasia factor from human urine. It is concluded that the changes produced by pyridoxine deficiency and by the urine fractions are not...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1950-12, Vol.75 (3), p.655-658
Hauptverfasser: Weir, David R., Heinle, Robert W.
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Cortisone
Humans
Leukemia
Metaplasia
Myeloproliferative Disorders
Old Medline
Primary Myelofibrosis
Splenic Diseases
Vitamin B 6
Vitamin B 6 Deficiency
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Zusammenfassung:Summary Similar hematologic and histologic changes occurred in mice made pyridoxine deficient, in mice treated with cortisone, and in mice treated with a myeloid metaplasia factor from human urine. It is concluded that the changes produced by pyridoxine deficiency and by the urine fractions are not necessarily mediated through the mechanism of the alarm reaction. Other mechanisms of action are considered.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-75-18295