Long-term treatment with clozapine on aging mice

To further clarify the relationship between central neurotransmitter systems, organ function and aging, we used mice to study the effects of long-term administration of the antipsychotic agent clozapine (10 and 20 mg/kg) on some age-related behavioral and organ-function tests. Compared to controls,...

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Veröffentlicht in:	Life sciences (1973) 1979-09, Vol.25 (10), p.865-872
Hauptverfasser:	Rolsten, Carolyn, Claghorn, James, Samorajski, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Body Weight - drug effects Clozapine - pharmacology Dibenzazepines - pharmacology Male Mice Mice, Inbred C57BL Motor Activity - drug effects Sleep - drug effects
Online-Zugang:	Volltext
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