A double-blind pediatric evaluation of levamisole in the prevention of recurrent upper respiratory tract infections

Levamisole was tested double-blind in 106 children with recurrent upper respiratory tract infections. They received either levamisole (n = 53) or placebo (n = 53) 0.5 ml/kg bodyweight b.i.d. for two consecutive days each week for six months. A control examination was performed every two months. Both...

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Veröffentlicht in:European journal of pediatrics 1979-09, Vol.131 (3), p.147-153
Hauptverfasser: Van Eygen, M, Dils, F, Gillerot, J, Verschueren, E
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container_title European journal of pediatrics
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creator Van Eygen, M
Dils, F
Gillerot, J
Verschueren, E
description Levamisole was tested double-blind in 106 children with recurrent upper respiratory tract infections. They received either levamisole (n = 53) or placebo (n = 53) 0.5 ml/kg bodyweight b.i.d. for two consecutive days each week for six months. A control examination was performed every two months. Both groups were compared by means of the Fisher-test and the Mann-Whitney U-test (two-tailed probability each). Improvement was observed more frequently in the levamisole group with regard to the number of episodes of infection, and the total duration and severity of the infections. No side-effects, except for some stomach complaints in one levamisole patient, were reported.
doi_str_mv 10.1007/BF00538939
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source MEDLINE; SpringerNature Journals
subjects Child
Double-Blind Method
Evaluation Studies as Topic
Female
Humans
Levamisole - therapeutic use
Male
Recurrence
Respiratory Tract Infections - prevention & control
title A double-blind pediatric evaluation of levamisole in the prevention of recurrent upper respiratory tract infections
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