The Langer-Giedion syndrome: report of a 22-year old woman
A 22-year-old woman with the Langer-Giedion syndrome and delayed puberty is presented. Pertinent features include a bulbous nose, sparse hair, protruding ears, multiple cartilaginous exostoses, cone-shaped phalangeal epiphyses, short stature, microcephaly, and mental retardation. She is the oldest p...
Gespeichert in:
| Veröffentlicht in: | Pediatrics (Evanston) 1979-10, Vol.64 (4), p.542-545 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 545 |
|---|---|
| container_issue | 4 |
| container_start_page | 542 |
| container_title | Pediatrics (Evanston) |
| container_volume | 64 |
| creator | Wilson, W G Herrington, R T Aylsworth, A S |
| description | A 22-year-old woman with the Langer-Giedion syndrome and delayed puberty is presented. Pertinent features include a bulbous nose, sparse hair, protruding ears, multiple cartilaginous exostoses, cone-shaped phalangeal epiphyses, short stature, microcephaly, and mental retardation. She is the oldest patient thus far described with this condition, and is compared to the ten previously published cases. The clinical course of patients with the Langer-Giedion syndrome and the possibility of malignant change in the exostoses have not been established. |
| doi_str_mv | 10.1542/peds.64.4.542 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_74712884</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>74712884</sourcerecordid><originalsourceid>FETCH-LOGICAL-c287t-893ff3f776a71544ac8a6851bad6ade0b0d7d4b68a41b77399dc75039a5b52da3</originalsourceid><addsrcrecordid>eNo9kM1LwzAchoP4NadHbx5y8paazybdTYZOoeBlnsOvTaqVtqnJhuy_X8eGp5cXHl5eHoTuGc2Ykvxp9C5lucxkNrUzNGO0MERyrc7RjFLBiKRUXaOblH4opVJpfoUuBVNUFjO0WH97XMLw5SNZtd61YcBpN7gYer_A0Y8hbnBoMGDOyc5DxKFz-C_0MNyiiwa65O9OOUefry_r5RspP1bvy-eS1NzoDTGFaBrRaJ2Dnv5KqA3kRrEKXA7O04o67WSVG5Cs0loUhau1oqIAVSnuQMzR43F3jOF369PG9m2qfdfB4MM2WS0148bICSRHsI4hpegbO8a2h7izjNqDKntQZXNppZ3axD-chrdV790_fXQj9ldJY0c</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74712884</pqid></control><display><type>article</type><title>The Langer-Giedion syndrome: report of a 22-year old woman</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Wilson, W G ; Herrington, R T ; Aylsworth, A S</creator><creatorcontrib>Wilson, W G ; Herrington, R T ; Aylsworth, A S</creatorcontrib><description>A 22-year-old woman with the Langer-Giedion syndrome and delayed puberty is presented. Pertinent features include a bulbous nose, sparse hair, protruding ears, multiple cartilaginous exostoses, cone-shaped phalangeal epiphyses, short stature, microcephaly, and mental retardation. She is the oldest patient thus far described with this condition, and is compared to the ten previously published cases. The clinical course of patients with the Langer-Giedion syndrome and the possibility of malignant change in the exostoses have not been established.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.64.4.542</identifier><identifier>PMID: 315049</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Epiphyses - abnormalities ; Exostoses, Multiple Hereditary - complications ; Face ; Female ; Growth Disorders - complications ; Humans ; Intellectual Disability - complications ; Microcephaly - complications ; Puberty ; Time Factors</subject><ispartof>Pediatrics (Evanston), 1979-10, Vol.64 (4), p.542-545</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c287t-893ff3f776a71544ac8a6851bad6ade0b0d7d4b68a41b77399dc75039a5b52da3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/315049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilson, W G</creatorcontrib><creatorcontrib>Herrington, R T</creatorcontrib><creatorcontrib>Aylsworth, A S</creatorcontrib><title>The Langer-Giedion syndrome: report of a 22-year old woman</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>A 22-year-old woman with the Langer-Giedion syndrome and delayed puberty is presented. Pertinent features include a bulbous nose, sparse hair, protruding ears, multiple cartilaginous exostoses, cone-shaped phalangeal epiphyses, short stature, microcephaly, and mental retardation. She is the oldest patient thus far described with this condition, and is compared to the ten previously published cases. The clinical course of patients with the Langer-Giedion syndrome and the possibility of malignant change in the exostoses have not been established.</description><subject>Adult</subject><subject>Epiphyses - abnormalities</subject><subject>Exostoses, Multiple Hereditary - complications</subject><subject>Face</subject><subject>Female</subject><subject>Growth Disorders - complications</subject><subject>Humans</subject><subject>Intellectual Disability - complications</subject><subject>Microcephaly - complications</subject><subject>Puberty</subject><subject>Time Factors</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM1LwzAchoP4NadHbx5y8paazybdTYZOoeBlnsOvTaqVtqnJhuy_X8eGp5cXHl5eHoTuGc2Ykvxp9C5lucxkNrUzNGO0MERyrc7RjFLBiKRUXaOblH4opVJpfoUuBVNUFjO0WH97XMLw5SNZtd61YcBpN7gYer_A0Y8hbnBoMGDOyc5DxKFz-C_0MNyiiwa65O9OOUefry_r5RspP1bvy-eS1NzoDTGFaBrRaJ2Dnv5KqA3kRrEKXA7O04o67WSVG5Cs0loUhau1oqIAVSnuQMzR43F3jOF369PG9m2qfdfB4MM2WS0148bICSRHsI4hpegbO8a2h7izjNqDKntQZXNppZ3axD-chrdV790_fXQj9ldJY0c</recordid><startdate>197910</startdate><enddate>197910</enddate><creator>Wilson, W G</creator><creator>Herrington, R T</creator><creator>Aylsworth, A S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197910</creationdate><title>The Langer-Giedion syndrome: report of a 22-year old woman</title><author>Wilson, W G ; Herrington, R T ; Aylsworth, A S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c287t-893ff3f776a71544ac8a6851bad6ade0b0d7d4b68a41b77399dc75039a5b52da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Epiphyses - abnormalities</topic><topic>Exostoses, Multiple Hereditary - complications</topic><topic>Face</topic><topic>Female</topic><topic>Growth Disorders - complications</topic><topic>Humans</topic><topic>Intellectual Disability - complications</topic><topic>Microcephaly - complications</topic><topic>Puberty</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilson, W G</creatorcontrib><creatorcontrib>Herrington, R T</creatorcontrib><creatorcontrib>Aylsworth, A S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics (Evanston)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilson, W G</au><au>Herrington, R T</au><au>Aylsworth, A S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Langer-Giedion syndrome: report of a 22-year old woman</atitle><jtitle>Pediatrics (Evanston)</jtitle><addtitle>Pediatrics</addtitle><date>1979-10</date><risdate>1979</risdate><volume>64</volume><issue>4</issue><spage>542</spage><epage>545</epage><pages>542-545</pages><issn>0031-4005</issn><eissn>1098-4275</eissn><abstract>A 22-year-old woman with the Langer-Giedion syndrome and delayed puberty is presented. Pertinent features include a bulbous nose, sparse hair, protruding ears, multiple cartilaginous exostoses, cone-shaped phalangeal epiphyses, short stature, microcephaly, and mental retardation. She is the oldest patient thus far described with this condition, and is compared to the ten previously published cases. The clinical course of patients with the Langer-Giedion syndrome and the possibility of malignant change in the exostoses have not been established.</abstract><cop>United States</cop><pmid>315049</pmid><doi>10.1542/peds.64.4.542</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0031-4005 |
| ispartof | Pediatrics (Evanston), 1979-10, Vol.64 (4), p.542-545 |
| issn | 0031-4005 1098-4275 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74712884 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Epiphyses - abnormalities Exostoses, Multiple Hereditary - complications Face Female Growth Disorders - complications Humans Intellectual Disability - complications Microcephaly - complications Puberty Time Factors |
| title | The Langer-Giedion syndrome: report of a 22-year old woman |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T03%3A39%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Langer-Giedion%20syndrome:%20report%20of%20a%2022-year%20old%20woman&rft.jtitle=Pediatrics%20(Evanston)&rft.au=Wilson,%20W%20G&rft.date=1979-10&rft.volume=64&rft.issue=4&rft.spage=542&rft.epage=545&rft.pages=542-545&rft.issn=0031-4005&rft.eissn=1098-4275&rft_id=info:doi/10.1542/peds.64.4.542&rft_dat=%3Cproquest_cross%3E74712884%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74712884&rft_id=info:pmid/315049&rfr_iscdi=true |