Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia
The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were ext...
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| Veröffentlicht in: | Lipids 1979-07, Vol.14 (7), p.691-694 |
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| creator | Jensen, R. G. Clark, R. M. Gerrior, S. A. Fey, M. B. Gotto, A. M. |
| description | The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters. |
| doi_str_mv | 10.1007/BF02533457 |
| format | Article |
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G. ; Clark, R. M. ; Gerrior, S. A. ; Fey, M. B. ; Gotto, A. M.</creator><creatorcontrib>Jensen, R. G. ; Clark, R. M. ; Gerrior, S. A. ; Fey, M. B. ; Gotto, A. M.</creatorcontrib><description>The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters.</description><identifier>ISSN: 0024-4201</identifier><identifier>EISSN: 1558-9307</identifier><identifier>DOI: 10.1007/BF02533457</identifier><identifier>PMID: 225633</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer‐Verlag</publisher><subject>Adult ; Cholesterol Esters - blood ; Chylomicrons - blood ; Fatty Acids - blood ; Female ; Humans ; Hyperlipidemias - blood ; Lipoproteins, HDL - blood ; Lipoproteins, LDL - blood ; Lipoproteins, VLDL - blood ; Male ; Middle Aged ; Sex Factors ; Triglycerides - blood</subject><ispartof>Lipids, 1979-07, Vol.14 (7), p.691-694</ispartof><rights>1979 American Oil Chemists' Society (AOCS)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3221-9576480ca695161ae153ff8e1686c4004b8c519b0cc898e783c28d09ddd7e3c33</citedby><cites>FETCH-LOGICAL-c3221-9576480ca695161ae153ff8e1686c4004b8c519b0cc898e783c28d09ddd7e3c33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/225633$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jensen, R. G.</creatorcontrib><creatorcontrib>Clark, R. M.</creatorcontrib><creatorcontrib>Gerrior, S. A.</creatorcontrib><creatorcontrib>Fey, M. B.</creatorcontrib><creatorcontrib>Gotto, A. M.</creatorcontrib><title>Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia</title><title>Lipids</title><addtitle>Lipids</addtitle><description>The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters.</description><subject>Adult</subject><subject>Cholesterol Esters - blood</subject><subject>Chylomicrons - blood</subject><subject>Fatty Acids - blood</subject><subject>Female</subject><subject>Humans</subject><subject>Hyperlipidemias - blood</subject><subject>Lipoproteins, HDL - blood</subject><subject>Lipoproteins, LDL - blood</subject><subject>Lipoproteins, VLDL - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Sex Factors</subject><subject>Triglycerides - blood</subject><issn>0024-4201</issn><issn>1558-9307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtPwzAUhS3EqxQWZgZPDEiB61fsjFBeRZVgANbItR1q5DTFToXy7wmkgo3p6Op8Orr6EDomcE4A5MXVLVDBGBdyC42IECorGMhtNAKgPOMUyD46SOm9PwkvxB7apVTkjI3Qw2TRBJdaF7uAfxLrpcVt9Np04S10xsUm4Eq3bYe18TZhv8Rtt3L4FS_6iMGvvHW114dop9IhuaNNjtHL7c3z5D6bPd5NJ5ezzDBKSVYImXMFRueFIDnRjghWVcqRXOWGA_C5MoIUczBGFcpJxQxVFgprrXTMMDZGp8PuKjYf6_7nsvbJuBD00jXrVEouCVApevBsAE1sUoquKlfR1zp2JYHy21v5562HTzar63nt7C86iOprGOpPH1z3z1A5mz5dQ14Q9gXnOnU9</recordid><startdate>197907</startdate><enddate>197907</enddate><creator>Jensen, R. 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M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3221-9576480ca695161ae153ff8e1686c4004b8c519b0cc898e783c28d09ddd7e3c33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Cholesterol Esters - blood</topic><topic>Chylomicrons - blood</topic><topic>Fatty Acids - blood</topic><topic>Female</topic><topic>Humans</topic><topic>Hyperlipidemias - blood</topic><topic>Lipoproteins, HDL - blood</topic><topic>Lipoproteins, LDL - blood</topic><topic>Lipoproteins, VLDL - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Sex Factors</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jensen, R. G.</creatorcontrib><creatorcontrib>Clark, R. M.</creatorcontrib><creatorcontrib>Gerrior, S. A.</creatorcontrib><creatorcontrib>Fey, M. B.</creatorcontrib><creatorcontrib>Gotto, A. M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jensen, R. G.</au><au>Clark, R. M.</au><au>Gerrior, S. A.</au><au>Fey, M. B.</au><au>Gotto, A. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia</atitle><jtitle>Lipids</jtitle><addtitle>Lipids</addtitle><date>1979-07</date><risdate>1979</risdate><volume>14</volume><issue>7</issue><spage>691</spage><epage>694</epage><pages>691-694</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer‐Verlag</pub><pmid>225633</pmid><doi>10.1007/BF02533457</doi><tpages>4</tpages></addata></record> |
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| subjects | Adult Cholesterol Esters - blood Chylomicrons - blood Fatty Acids - blood Female Humans Hyperlipidemias - blood Lipoproteins, HDL - blood Lipoproteins, LDL - blood Lipoproteins, VLDL - blood Male Middle Aged Sex Factors Triglycerides - blood |
| title | Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia |
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