Tumor uptake of radiolabeled pyrimidine bases and pyrimidine nucleosides in animal models—I. 6-[ 3H]-5-fluorouracil

The differential tissue distribution and urinary excretion of small intravenous doses (4 μg kg −1) of 6-[ 3H]-5-fluorouracil have been studied in two strains of mice bearing transplantable tumors. The subcutaneous Lewis Lung carcinoma and the solid Ehrlich Ascites carcinoma both retained less than 1...

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Veröffentlicht in:	International journal of nuclear medicine & biology 1979, Vol.6 (2), p.97-101
Hauptverfasser:	Abrams, D.N., Knaus, E.E., Wiebe, L.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinoma, Ehrlich Tumor - metabolism Carcinoma, Ehrlich Tumor - urine Fluorouracil - metabolism Fluorouracil - urine Half-Life Lung Neoplasms - metabolism Lung Neoplasms - urine Male Mice Models, Biological Neoplasm Transplantation Neoplasms, Experimental - metabolism Neoplasms, Experimental - urine Pyrimidine Nucleosides - metabolism Pyrimidine Nucleosides - urine Time Factors Tritium
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