Increased gonadotropin levels in newborn premature females treated by phototherapy
A group of 16 premature infants (9 females and 7 males) who were treated with phototherapy because of jaundice were compared in respect of plasma gonadotropin levels to a control group of 10 premature infants (4 girls and 6 boys) who did not require phototherapy. Luteinizing hormone (LH) and follicl...
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| Veröffentlicht in: | Journal of steroid biochemistry 1979-03, Vol.10 (3), p.335-337 |
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| container_title | Journal of steroid biochemistry |
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| creator | Lemaitre, B.J. Toubas, P.L. Dreux, C. Minkowski, A. |
| description | A group of 16 premature infants (9 females and 7 males) who were treated with phototherapy because of jaundice were compared in respect of plasma gonadotropin levels to a control group of 10 premature infants (4 girls and 6 boys) who did not require phototherapy. Luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured by radioimmunoassay. During the third and fourth week of life, gonadotropins increased simultaneously in phototherapy treated females (FSH
P < 0.001; LH
P < 0.01), reached high values (20 and 80 mU/ml, respectively), stayed elevated during three weeks, then declined quickly to under 10 mU/ml. In the group of treated males no significant rise in FSH and LH was observed. Constant phototherapy and/or the sudden stopping of this treatment in the jaundiced premature newborn female is responsible for a marked and transient elevation of gonadotropins. |
| doi_str_mv | 10.1016/0022-4731(79)90261-9 |
| format | Article |
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P < 0.001; LH
P < 0.01), reached high values (20 and 80 mU/ml, respectively), stayed elevated during three weeks, then declined quickly to under 10 mU/ml. In the group of treated males no significant rise in FSH and LH was observed. Constant phototherapy and/or the sudden stopping of this treatment in the jaundiced premature newborn female is responsible for a marked and transient elevation of gonadotropins.</description><identifier>ISSN: 0022-4731</identifier><identifier>DOI: 10.1016/0022-4731(79)90261-9</identifier><identifier>PMID: 459496</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Female ; Humans ; Infant, Newborn ; Infant, Premature, Diseases - blood ; Infant, Premature, Diseases - therapy ; Jaundice, Neonatal - blood ; Jaundice, Neonatal - therapy ; Luteinizing Hormone - blood ; Male ; Phototherapy ; Time Factors</subject><ispartof>Journal of steroid biochemistry, 1979-03, Vol.10 (3), p.335-337</ispartof><rights>1979</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-e063943c6e194a6dd01392c26e534de3db2c511cb03f9782b007fe9e407dd1f43</citedby><cites>FETCH-LOGICAL-c356t-e063943c6e194a6dd01392c26e534de3db2c511cb03f9782b007fe9e407dd1f43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/459496$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lemaitre, B.J.</creatorcontrib><creatorcontrib>Toubas, P.L.</creatorcontrib><creatorcontrib>Dreux, C.</creatorcontrib><creatorcontrib>Minkowski, A.</creatorcontrib><title>Increased gonadotropin levels in newborn premature females treated by phototherapy</title><title>Journal of steroid biochemistry</title><addtitle>J Steroid Biochem</addtitle><description>A group of 16 premature infants (9 females and 7 males) who were treated with phototherapy because of jaundice were compared in respect of plasma gonadotropin levels to a control group of 10 premature infants (4 girls and 6 boys) who did not require phototherapy. Luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured by radioimmunoassay. During the third and fourth week of life, gonadotropins increased simultaneously in phototherapy treated females (FSH
P < 0.001; LH
P < 0.01), reached high values (20 and 80 mU/ml, respectively), stayed elevated during three weeks, then declined quickly to under 10 mU/ml. In the group of treated males no significant rise in FSH and LH was observed. Constant phototherapy and/or the sudden stopping of this treatment in the jaundiced premature newborn female is responsible for a marked and transient elevation of gonadotropins.</description><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature, Diseases - blood</subject><subject>Infant, Premature, Diseases - therapy</subject><subject>Jaundice, Neonatal - blood</subject><subject>Jaundice, Neonatal - therapy</subject><subject>Luteinizing Hormone - blood</subject><subject>Male</subject><subject>Phototherapy</subject><subject>Time Factors</subject><issn>0022-4731</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLtOwzAUhj1wK4U36JAJwRDwLU69IKGKS6VKSAhmK7FPaFASB9sp6tvjkqoj0_l1_svwITQj-JZgIu4wpjTlOSPXubyRmAqSyiM0ObzP0Ln3XxgTOef0FJ3wTHIpJuht2WkHhQeTfNquMDY429dd0sAGGp9E1cFPaV2X9A7aIgwOkiqKBnwSYjHEYrlN-rUNNqzBFf32Ah1XRePhcn-n6OPp8X3xkq5en5eLh1WqWSZCClgwyZkWQCQvhDGYMEk1FZAxboCZkuqMEF1iVsl8TkuM8wokcJwbQyrOpuhq3O2d_R7AB9XWXkPTFB3YwaucC06yOY1BPga1s947qFTv6rZwW0Ww2tFTO0xqh0nlUv3RUzLWZvv9oWzBHEojumjfj3bkBJsanPK6hk6DqR3ooIyt_9__BVJQgWE</recordid><startdate>197903</startdate><enddate>197903</enddate><creator>Lemaitre, B.J.</creator><creator>Toubas, P.L.</creator><creator>Dreux, C.</creator><creator>Minkowski, A.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197903</creationdate><title>Increased gonadotropin levels in newborn premature females treated by phototherapy</title><author>Lemaitre, B.J. ; Toubas, P.L. ; Dreux, C. ; Minkowski, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-e063943c6e194a6dd01392c26e534de3db2c511cb03f9782b007fe9e407dd1f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Female</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature, Diseases - blood</topic><topic>Infant, Premature, Diseases - therapy</topic><topic>Jaundice, Neonatal - blood</topic><topic>Jaundice, Neonatal - therapy</topic><topic>Luteinizing Hormone - blood</topic><topic>Male</topic><topic>Phototherapy</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lemaitre, B.J.</creatorcontrib><creatorcontrib>Toubas, P.L.</creatorcontrib><creatorcontrib>Dreux, C.</creatorcontrib><creatorcontrib>Minkowski, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of steroid biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lemaitre, B.J.</au><au>Toubas, P.L.</au><au>Dreux, C.</au><au>Minkowski, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased gonadotropin levels in newborn premature females treated by phototherapy</atitle><jtitle>Journal of steroid biochemistry</jtitle><addtitle>J Steroid Biochem</addtitle><date>1979-03</date><risdate>1979</risdate><volume>10</volume><issue>3</issue><spage>335</spage><epage>337</epage><pages>335-337</pages><issn>0022-4731</issn><abstract>A group of 16 premature infants (9 females and 7 males) who were treated with phototherapy because of jaundice were compared in respect of plasma gonadotropin levels to a control group of 10 premature infants (4 girls and 6 boys) who did not require phototherapy. Luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured by radioimmunoassay. During the third and fourth week of life, gonadotropins increased simultaneously in phototherapy treated females (FSH
P < 0.001; LH
P < 0.01), reached high values (20 and 80 mU/ml, respectively), stayed elevated during three weeks, then declined quickly to under 10 mU/ml. In the group of treated males no significant rise in FSH and LH was observed. Constant phototherapy and/or the sudden stopping of this treatment in the jaundiced premature newborn female is responsible for a marked and transient elevation of gonadotropins.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>459496</pmid><doi>10.1016/0022-4731(79)90261-9</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of steroid biochemistry, 1979-03, Vol.10 (3), p.335-337 |
| issn | 0022-4731 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Female Humans Infant, Newborn Infant, Premature, Diseases - blood Infant, Premature, Diseases - therapy Jaundice, Neonatal - blood Jaundice, Neonatal - therapy Luteinizing Hormone - blood Male Phototherapy Time Factors |
| title | Increased gonadotropin levels in newborn premature females treated by phototherapy |
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