Seronegative HIV-1 infection: a review of the literature
HIV-1-specific antibodies can be detected in HIV-1-positive patients within weeks of primary infection. Rare cases have been reported of patients who are persistently seronegative despite evidence of HIV-1 infection. We present a retrospective review of the clinical, virologic and immunologic charac...
Gespeichert in:
| Veröffentlicht in: | AIDS (London) 2010-06, Vol.24 (10), p.1407-1414 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1414 |
|---|---|
| container_issue | 10 |
| container_start_page | 1407 |
| container_title | AIDS (London) |
| container_volume | 24 |
| creator | SPIVAK, Adam M SYDNOR, Emily R. M BLANKSON, Joel N GALLANT, Joel E |
| description | HIV-1-specific antibodies can be detected in HIV-1-positive patients within weeks of primary infection. Rare cases have been reported of patients who are persistently seronegative despite evidence of HIV-1 infection. We present a retrospective review of the clinical, virologic and immunologic characteristics of 25 persistently seronegative patients whose cases have been published to date and postulate a biologic mechanism for this phenomenon. |
| doi_str_mv | 10.1097/QAD.0b013e32833ac65c |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_746314651</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733281699</sourcerecordid><originalsourceid>FETCH-LOGICAL-c414t-7e6263b4f7b6fb8317a66739185f7e0557125c0133d0e8a2184364aaa18b0e4e3</originalsourceid><addsrcrecordid>eNqFkMtOwzAQRS0EoqXwBwhlg1iljB-xHXZVeVWqhBCPbeS4YzBKk2KnRfw9qVpAYsNqNufemTmEHFMYUsjV-f3ocgglUI6cac6NlZndIX0qFE-zTNFd0gcm8zTnCnrkIMY3AMhA633SYyCkYlr1iX7A0NT4Ylq_wuR28pzSxNcObeub-iIxScCVx4-kcUn7iknlWwymXQY8JHvOVBGPtnNAnq6vHse36fTuZjIeTVMrqGhThZJJXgqnSulKzakyUiqeU505hbA-lGW2-4LPALVhVAsuhTGG6hJQIB-Qs03vIjTvS4xtMffRYlWZGptlLJSQnAqZ0f9J3omiMs87UmxIG5oYA7piEfzchM-CQrGWW3Ryi79yu9jJdsGynOPsJ_RtswNOt4CJ1lQumNr6-MuxXAjQwL8AZ4WAZQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733281699</pqid></control><display><type>article</type><title>Seronegative HIV-1 infection: a review of the literature</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Journals@Ovid Complete</source><creator>SPIVAK, Adam M ; SYDNOR, Emily R. M ; BLANKSON, Joel N ; GALLANT, Joel E</creator><creatorcontrib>SPIVAK, Adam M ; SYDNOR, Emily R. M ; BLANKSON, Joel N ; GALLANT, Joel E</creatorcontrib><description>HIV-1-specific antibodies can be detected in HIV-1-positive patients within weeks of primary infection. Rare cases have been reported of patients who are persistently seronegative despite evidence of HIV-1 infection. We present a retrospective review of the clinical, virologic and immunologic characteristics of 25 persistently seronegative patients whose cases have been published to date and postulate a biologic mechanism for this phenomenon.</description><identifier>ISSN: 0269-9370</identifier><identifier>EISSN: 1473-5571</identifier><identifier>DOI: 10.1097/QAD.0b013e32833ac65c</identifier><identifier>PMID: 20467287</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Adult ; AIDS/HIV ; Antibodies ; Biological and medical sciences ; CD4 Lymphocyte Count ; Disease Progression ; Female ; HIV Antibodies - immunology ; HIV Seronegativity - immunology ; HIV Seropositivity - immunology ; HIV-1 - immunology ; Human immunodeficiency virus 1 ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Infant ; Infection ; Infectious diseases ; Male ; Medical sciences ; Middle Aged ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Viral Load ; Young Adult</subject><ispartof>AIDS (London), 2010-06, Vol.24 (10), p.1407-1414</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-7e6263b4f7b6fb8317a66739185f7e0557125c0133d0e8a2184364aaa18b0e4e3</citedby><cites>FETCH-LOGICAL-c414t-7e6263b4f7b6fb8317a66739185f7e0557125c0133d0e8a2184364aaa18b0e4e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22944080$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20467287$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SPIVAK, Adam M</creatorcontrib><creatorcontrib>SYDNOR, Emily R. M</creatorcontrib><creatorcontrib>BLANKSON, Joel N</creatorcontrib><creatorcontrib>GALLANT, Joel E</creatorcontrib><title>Seronegative HIV-1 infection: a review of the literature</title><title>AIDS (London)</title><addtitle>AIDS</addtitle><description>HIV-1-specific antibodies can be detected in HIV-1-positive patients within weeks of primary infection. Rare cases have been reported of patients who are persistently seronegative despite evidence of HIV-1 infection. We present a retrospective review of the clinical, virologic and immunologic characteristics of 25 persistently seronegative patients whose cases have been published to date and postulate a biologic mechanism for this phenomenon.</description><subject>Adolescent</subject><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Antibodies</subject><subject>Biological and medical sciences</subject><subject>CD4 Lymphocyte Count</subject><subject>Disease Progression</subject><subject>Female</subject><subject>HIV Antibodies - immunology</subject><subject>HIV Seronegativity - immunology</subject><subject>HIV Seropositivity - immunology</subject><subject>HIV-1 - immunology</subject><subject>Human immunodeficiency virus 1</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infant</subject><subject>Infection</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Viral Load</subject><subject>Young Adult</subject><issn>0269-9370</issn><issn>1473-5571</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EoqXwBwhlg1iljB-xHXZVeVWqhBCPbeS4YzBKk2KnRfw9qVpAYsNqNufemTmEHFMYUsjV-f3ocgglUI6cac6NlZndIX0qFE-zTNFd0gcm8zTnCnrkIMY3AMhA633SYyCkYlr1iX7A0NT4Ylq_wuR28pzSxNcObeub-iIxScCVx4-kcUn7iknlWwymXQY8JHvOVBGPtnNAnq6vHse36fTuZjIeTVMrqGhThZJJXgqnSulKzakyUiqeU505hbA-lGW2-4LPALVhVAsuhTGG6hJQIB-Qs03vIjTvS4xtMffRYlWZGptlLJSQnAqZ0f9J3omiMs87UmxIG5oYA7piEfzchM-CQrGWW3Ryi79yu9jJdsGynOPsJ_RtswNOt4CJ1lQumNr6-MuxXAjQwL8AZ4WAZQ</recordid><startdate>20100619</startdate><enddate>20100619</enddate><creator>SPIVAK, Adam M</creator><creator>SYDNOR, Emily R. M</creator><creator>BLANKSON, Joel N</creator><creator>GALLANT, Joel E</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>20100619</creationdate><title>Seronegative HIV-1 infection: a review of the literature</title><author>SPIVAK, Adam M ; SYDNOR, Emily R. M ; BLANKSON, Joel N ; GALLANT, Joel E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-7e6263b4f7b6fb8317a66739185f7e0557125c0133d0e8a2184364aaa18b0e4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>AIDS/HIV</topic><topic>Antibodies</topic><topic>Biological and medical sciences</topic><topic>CD4 Lymphocyte Count</topic><topic>Disease Progression</topic><topic>Female</topic><topic>HIV Antibodies - immunology</topic><topic>HIV Seronegativity - immunology</topic><topic>HIV Seropositivity - immunology</topic><topic>HIV-1 - immunology</topic><topic>Human immunodeficiency virus 1</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infant</topic><topic>Infection</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><topic>Viral Load</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SPIVAK, Adam M</creatorcontrib><creatorcontrib>SYDNOR, Emily R. M</creatorcontrib><creatorcontrib>BLANKSON, Joel N</creatorcontrib><creatorcontrib>GALLANT, Joel E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>AIDS (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SPIVAK, Adam M</au><au>SYDNOR, Emily R. M</au><au>BLANKSON, Joel N</au><au>GALLANT, Joel E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seronegative HIV-1 infection: a review of the literature</atitle><jtitle>AIDS (London)</jtitle><addtitle>AIDS</addtitle><date>2010-06-19</date><risdate>2010</risdate><volume>24</volume><issue>10</issue><spage>1407</spage><epage>1414</epage><pages>1407-1414</pages><issn>0269-9370</issn><eissn>1473-5571</eissn><abstract>HIV-1-specific antibodies can be detected in HIV-1-positive patients within weeks of primary infection. Rare cases have been reported of patients who are persistently seronegative despite evidence of HIV-1 infection. We present a retrospective review of the clinical, virologic and immunologic characteristics of 25 persistently seronegative patients whose cases have been published to date and postulate a biologic mechanism for this phenomenon.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>20467287</pmid><doi>10.1097/QAD.0b013e32833ac65c</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0269-9370 |
| ispartof | AIDS (London), 2010-06, Vol.24 (10), p.1407-1414 |
| issn | 0269-9370 1473-5571 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_746314651 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Adolescent Adult AIDS/HIV Antibodies Biological and medical sciences CD4 Lymphocyte Count Disease Progression Female HIV Antibodies - immunology HIV Seronegativity - immunology HIV Seropositivity - immunology HIV-1 - immunology Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infant Infection Infectious diseases Male Medical sciences Middle Aged Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Young Adult |
| title | Seronegative HIV-1 infection: a review of the literature |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T18%3A05%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Seronegative%20HIV-1%20infection:%20a%20review%20of%20the%20literature&rft.jtitle=AIDS%20(London)&rft.au=SPIVAK,%20Adam%20M&rft.date=2010-06-19&rft.volume=24&rft.issue=10&rft.spage=1407&rft.epage=1414&rft.pages=1407-1414&rft.issn=0269-9370&rft.eissn=1473-5571&rft_id=info:doi/10.1097/QAD.0b013e32833ac65c&rft_dat=%3Cproquest_cross%3E733281699%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733281699&rft_id=info:pmid/20467287&rfr_iscdi=true |