Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks

Gene therapy for neurological, and in particular neurodegenerative, disease is now a reality. A number of early phase clinical trials have been completed and several are currently in progress. In view of this, it is critically important to evaluate the immunological risk associated with neurological...

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Veröffentlicht in:	Gene therapy 2010-04, Vol.17 (4), p.448-458
Hauptverfasser:	McMenamin, M M, Wood, M J A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/2300/1514 631/378/371 631/61/201 692/699/375/365 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Applied cell therapy and gene therapy Biological and medical sciences Biomedical and Life Sciences Biomedicine Biotechnology Cell Biology Central nervous system Central Nervous System - immunology Clinical trials Degeneration Expression vectors Fundamental and applied biological sciences. Psychology Gene Expression Gene Silencing - physiology Gene Therapy Gene transfer Gene Transfer Techniques Genetic research Genetic Therapy - methods Genetic Vectors - genetics Genetic Vectors - immunology Health. Pharmaceutical industry Human Genetics Humans Immunity, Innate - immunology Immunology Immunoregulation Industrial applications and implications. Economical aspects Medical sciences Models, Biological Nanotechnology Nervous system Neurodegenerative diseases Neurodegenerative Diseases - genetics Neurodegenerative Diseases - immunology Neurodegenerative Diseases - therapy Neurological disorders Physiological aspects review Risk factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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