Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects

Context: Very limited information is available regarding the function of human thyroid hormone responsive Spot 14 (human S14, hS14) in adipogenesis and human adiposity. Objective: To evaluate hS14 levels during differentiation of human pre-adipocytes, in human fat depots and isolated fat cells. Desi...

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Veröffentlicht in:	International Journal of Obesity 2010-03, Vol.34 (3), p.487-499
Hauptverfasser:	Ortega, F.J, Vazquez-Martin, A, Moreno-Navarrete, J.M, Bassols, J, Rodriguez-Hermosa, J, Girones, J, Ricart, W, Peral, B, Tinahones, F.J, Fruhbeck, G, Menendez, J.A, Fernandez-Real, J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes Adipocytes - cytology Adipocytes - metabolism Adipogenesis - genetics Adipose tissue Adipose Tissue - metabolism Adipose tissues Animals Automation Biological and medical sciences Blood pressure Blotting, Western Body fat body mass index Care and treatment cell differentiation Cell Differentiation - genetics Cells, Cultured Cross-Sectional Studies Diabetes Down-Regulation Endocrinology Epidemiology Fatty acids Gene Expression gene expression regulation genes Genetic aspects Glucose Health Promotion and Disease Prevention human diseases Humans Internal Medicine Kinases lipogenesis Medical sciences Medicine Medicine & Public Health messenger RNA Metabolic Diseases Mice Nuclear Proteins - genetics Nuclear Proteins - metabolism Nutrition Obesity Obesity - metabolism Omentum - metabolism original-article overweight Overweight - metabolism Physiological aspects pre-adipocytes Proteins Public Health Reverse Transcriptase Polymerase Chain Reaction subcutaneous fat Subcutaneous Fat - metabolism systolic blood pressure Thyroid Thyroid gland Thyroid Hormone Receptors alpha - genetics Thyroid Hormone Receptors alpha - metabolism Thyroid hormones Transcription Factors - genetics Transcription Factors - metabolism visceral fat waist-to-hip ratio
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