Peripheral contributions to the mechanical hyperalgesia following a lumbar 5 spinal nerve lesion in rats

Abstract Using lumbar 5 (L5) dorsal root rhizotomy-bearing rats, we examined the extent to which L5 spinal nerve lesion (SNL)-induced mechanical hyperalgesia was governed by two peripheral components, that is Wallerian degeneration (WD) and peripherally-propagating injury discharge (PID). The contri...

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Veröffentlicht in:	Neuroscience 2010-01, Vol.165 (1), p.221-232
Hauptverfasser:	Jang, J.H, Lee, B.H, Nam, T.S, Kim, J.W, Kim, D.W, Leem, J.W
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals antidromic stimulation Electric Stimulation Hyperalgesia - physiopathology injury discharge Lumbosacral Region Male mechanical hyperalgesia Nerve Fibers, Unmyelinated - physiology nerve injury Neurology neuropathic pain Rats Rats, Wistar Spinal Nerves - injuries Spinal Nerves - physiopathology Touch Wallerian degeneration
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