Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette–Guérin (BCG) Tokyo 172: A comparative study of BCG vaccine substrains

Abstract To investigate the molecular characteristics of bacillus Calmette–Guérin (BCG) vaccines, the complete genomic sequence of Mycobacterium bovis BCG Tokyo 172 was determined, and the results were compared with those for BCG Pasteur and other M. tuberculosis complex. The genome of BCG Tokyo had...

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Veröffentlicht in:	Vaccine 2009-03, Vol.27 (11), p.1710-1716
Hauptverfasser:	Seki, Masaaki, Honda, Ikuro, Fujita, Isao, Yano, Ikuya, Yamamoto, Saburo, Koyama, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Applied microbiology Bacterial diseases Bacteriology Base Sequence BCG Tokyo BCG Vaccine - genetics Biological and medical sciences Complete genomic sequence DNA, Bacterial - genetics Fundamental and applied biological sciences. Psychology Genes, Bacterial - genetics Genetic differences Genome, Bacterial - genetics Human bacterial diseases Infectious diseases Medical sciences Microbiology Minisatellite Repeats Miscellaneous Molecular Sequence Data Mycobacterium bovis Mycobacterium bovis - genetics Polymorphism, Single Nucleotide Species Specificity Tuberculosis and atypical mycobacterial infections Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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