Social support and immunosuppressant therapy adherence among adult renal transplant recipients

Chisholm‐Burns MA, Spivey CA, Wilks SE. Social support and immunosuppressant therapy adherence among adult renal transplant recipients.
Clin Transplant 2010: 24: 312–320. © 2009 John Wiley & Sons A/S. :  Background:  The purpose of the study was to assess the relationship between social support...

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Veröffentlicht in:Clinical transplantation 2010-05, Vol.24 (3), p.312-320
Hauptverfasser: Chisholm-Burns, Marie A., Spivey, Christina A., Wilks, Scott E.
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container_start_page 312
container_title Clinical transplantation
container_volume 24
creator Chisholm-Burns, Marie A.
Spivey, Christina A.
Wilks, Scott E.
description Chisholm‐Burns MA, Spivey CA, Wilks SE. Social support and immunosuppressant therapy adherence among adult renal transplant recipients.
Clin Transplant 2010: 24: 312–320. © 2009 John Wiley & Sons A/S. :  Background:  The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. Methods:  A cross‐sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosuppressant Therapy Adherence Scale© (ITAS©) and Modified Social Support Survey (MSSS‐5). The correlation between ITAS© and MSSS‐5 summary scores was assessed using the correlation coefficient (r). Analyses of the following relationships were conducted using correlation coefficients: (i) ITAS© summary score and individual items of the MSSS‐5; and (ii) MSSS‐5 summary score and individual items of the ITAS©. A hierarchical regression was conducted. Results:  The response rate was 74%. The relationship between social support and adherence was significant (r = 0.214, p 
doi_str_mv 10.1111/j.1399-0012.2009.01060.x
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Clin Transplant 2010: 24: 312–320. © 2009 John Wiley &amp; Sons A/S. :  Background:  The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. Methods:  A cross‐sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosuppressant Therapy Adherence Scale© (ITAS©) and Modified Social Support Survey (MSSS‐5). The correlation between ITAS© and MSSS‐5 summary scores was assessed using the correlation coefficient (r). Analyses of the following relationships were conducted using correlation coefficients: (i) ITAS© summary score and individual items of the MSSS‐5; and (ii) MSSS‐5 summary score and individual items of the ITAS©. A hierarchical regression was conducted. Results:  The response rate was 74%. The relationship between social support and adherence was significant (r = 0.214, p &lt; 0.05). Two MSSS‐5 items (affectionate support and instrumental support pertaining to household functions) were related to ITAS© summary score (p &lt; 0.05), and one ITAS© item (forgetfulness) was related to the MSSS‐5 summary score (p &lt; 0.05). The regression model (all MSSS‐5 items) accounted for 24% of the variation in ITAS© summary scores. Conclusions:  The findings suggest that strategies utilizing social support to address forgetfulness as well as strategies to improve affectionate support and instrumental support related to daily household functions may be useful adherence intervention tools.</description><identifier>ISSN: 0902-0063</identifier><identifier>EISSN: 1399-0012</identifier><identifier>DOI: 10.1111/j.1399-0012.2009.01060.x</identifier><identifier>PMID: 19694770</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Biological and medical sciences ; Cross-Sectional Studies ; Female ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Humans ; immunosuppressant therapy ; Immunosuppressive Agents - therapeutic use ; Kidney Transplantation ; Male ; Medical sciences ; medication adherence ; Medication Adherence - statistics &amp; numerical data ; Middle Aged ; Patient Compliance ; renal transplant recipients ; Resilience, Psychological ; Social Support ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surveys and Questionnaires ; Tissue, organ and graft immunology</subject><ispartof>Clinical transplantation, 2010-05, Vol.24 (3), p.312-320</ispartof><rights>2009 John Wiley &amp; Sons A/S</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4680-5133b3888ffd68c570fc4a2b279664fa1eb6dbcf4f3b5c2347ac911e91be40553</citedby><cites>FETCH-LOGICAL-c4680-5133b3888ffd68c570fc4a2b279664fa1eb6dbcf4f3b5c2347ac911e91be40553</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1399-0012.2009.01060.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1399-0012.2009.01060.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=22857495$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19694770$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chisholm-Burns, Marie A.</creatorcontrib><creatorcontrib>Spivey, Christina A.</creatorcontrib><creatorcontrib>Wilks, Scott E.</creatorcontrib><title>Social support and immunosuppressant therapy adherence among adult renal transplant recipients</title><title>Clinical transplantation</title><addtitle>Clin Transplant</addtitle><description>Chisholm‐Burns MA, Spivey CA, Wilks SE. Social support and immunosuppressant therapy adherence among adult renal transplant recipients.
Clin Transplant 2010: 24: 312–320. © 2009 John Wiley &amp; Sons A/S. :  Background:  The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. Methods:  A cross‐sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosuppressant Therapy Adherence Scale© (ITAS©) and Modified Social Support Survey (MSSS‐5). The correlation between ITAS© and MSSS‐5 summary scores was assessed using the correlation coefficient (r). Analyses of the following relationships were conducted using correlation coefficients: (i) ITAS© summary score and individual items of the MSSS‐5; and (ii) MSSS‐5 summary score and individual items of the ITAS©. A hierarchical regression was conducted. Results:  The response rate was 74%. The relationship between social support and adherence was significant (r = 0.214, p &lt; 0.05). Two MSSS‐5 items (affectionate support and instrumental support pertaining to household functions) were related to ITAS© summary score (p &lt; 0.05), and one ITAS© item (forgetfulness) was related to the MSSS‐5 summary score (p &lt; 0.05). The regression model (all MSSS‐5 items) accounted for 24% of the variation in ITAS© summary scores. Conclusions:  The findings suggest that strategies utilizing social support to address forgetfulness as well as strategies to improve affectionate support and instrumental support related to daily household functions may be useful adherence intervention tools.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Humans</subject><subject>immunosuppressant therapy</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Kidney Transplantation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>medication adherence</subject><subject>Medication Adherence - statistics &amp; numerical data</subject><subject>Middle Aged</subject><subject>Patient Compliance</subject><subject>renal transplant recipients</subject><subject>Resilience, Psychological</subject><subject>Social Support</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surveys and Questionnaires</subject><subject>Tissue, organ and graft immunology</subject><issn>0902-0063</issn><issn>1399-0012</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcluFDEQhi0EIkPgFVBfEKduvC8HDmhEJkghKAuCE5bbbYOH3rC7lZm3x82Mhmt8cVX5-8ulvwAoEKxQPu-2FSJKlRAiXGEIVQUR5LDaPQGr08NTsIIK4hxzcgZepLTNVY44ew7OkOKKCgFX4MfdYINpizSP4xCnwvRNEbpu7oelEl1Kpp-K6ZeLZtwXpsmB660rTDf0P3M-t1ORK7nDFE2fxnbBo7NhDK6f0kvwzJs2uVfH-xx8vfh4v74sr75sPq0_XJWWcglLhgipiZTS-4ZLywT0lhpcY6E4p94gV_Omtp56UjOLCRXGKoScQrWjkDFyDt4e-o5x-DO7NOkuJOvaPI4b5qQF5ZhgSR9BEsIUJUxmUh5IG4eUovN6jKEzca8R1Msa9FYvbuvFbb2sQf9bg95l6evjJ3Pduea_8Oh7Bt4cAZOsaX32zoZ04jCWTFC1TPv-wD2E1u0fPYBe398uUdaXB31Ik9ud9Cb-1lwQwfS3642-ufuO2OfNtb4kfwHCKbOt</recordid><startdate>201005</startdate><enddate>201005</enddate><creator>Chisholm-Burns, Marie A.</creator><creator>Spivey, Christina A.</creator><creator>Wilks, Scott E.</creator><general>Blackwell Publishing Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>201005</creationdate><title>Social support and immunosuppressant therapy adherence among adult renal transplant recipients</title><author>Chisholm-Burns, Marie A. ; Spivey, Christina A. ; Wilks, Scott E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4680-5133b3888ffd68c570fc4a2b279664fa1eb6dbcf4f3b5c2347ac911e91be40553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Humans</topic><topic>immunosuppressant therapy</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Kidney Transplantation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>medication adherence</topic><topic>Medication Adherence - statistics &amp; numerical data</topic><topic>Middle Aged</topic><topic>Patient Compliance</topic><topic>renal transplant recipients</topic><topic>Resilience, Psychological</topic><topic>Social Support</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surveys and Questionnaires</topic><topic>Tissue, organ and graft immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chisholm-Burns, Marie A.</creatorcontrib><creatorcontrib>Spivey, Christina A.</creatorcontrib><creatorcontrib>Wilks, Scott E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Clinical transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chisholm-Burns, Marie A.</au><au>Spivey, Christina A.</au><au>Wilks, Scott E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Social support and immunosuppressant therapy adherence among adult renal transplant recipients</atitle><jtitle>Clinical transplantation</jtitle><addtitle>Clin Transplant</addtitle><date>2010-05</date><risdate>2010</risdate><volume>24</volume><issue>3</issue><spage>312</spage><epage>320</epage><pages>312-320</pages><issn>0902-0063</issn><eissn>1399-0012</eissn><abstract>Chisholm‐Burns MA, Spivey CA, Wilks SE. Social support and immunosuppressant therapy adherence among adult renal transplant recipients.
Clin Transplant 2010: 24: 312–320. © 2009 John Wiley &amp; Sons A/S. :  Background:  The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. Methods:  A cross‐sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosuppressant Therapy Adherence Scale© (ITAS©) and Modified Social Support Survey (MSSS‐5). The correlation between ITAS© and MSSS‐5 summary scores was assessed using the correlation coefficient (r). Analyses of the following relationships were conducted using correlation coefficients: (i) ITAS© summary score and individual items of the MSSS‐5; and (ii) MSSS‐5 summary score and individual items of the ITAS©. A hierarchical regression was conducted. Results:  The response rate was 74%. The relationship between social support and adherence was significant (r = 0.214, p &lt; 0.05). Two MSSS‐5 items (affectionate support and instrumental support pertaining to household functions) were related to ITAS© summary score (p &lt; 0.05), and one ITAS© item (forgetfulness) was related to the MSSS‐5 summary score (p &lt; 0.05). The regression model (all MSSS‐5 items) accounted for 24% of the variation in ITAS© summary scores. Conclusions:  The findings suggest that strategies utilizing social support to address forgetfulness as well as strategies to improve affectionate support and instrumental support related to daily household functions may be useful adherence intervention tools.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19694770</pmid><doi>10.1111/j.1399-0012.2009.01060.x</doi><tpages>9</tpages></addata></record>
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subjects Adult
Biological and medical sciences
Cross-Sectional Studies
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Humans
immunosuppressant therapy
Immunosuppressive Agents - therapeutic use
Kidney Transplantation
Male
Medical sciences
medication adherence
Medication Adherence - statistics & numerical data
Middle Aged
Patient Compliance
renal transplant recipients
Resilience, Psychological
Social Support
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surveys and Questionnaires
Tissue, organ and graft immunology
title Social support and immunosuppressant therapy adherence among adult renal transplant recipients
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