Ca sub()V.2 b-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

Excessive activation of calmodulin kinase II (CaMKII) causes arrhythmias and heart failure, but the cellular mechanisms for CaMKII-targeted proteins causing disordered cell membrane excitability and myocardial dysfunction remain uncertain. Failing human cardiomyocytes exhibit increased CaMKII and vo...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-01, Vol.107 (11), p.4996-5000
Hauptverfasser:	Koval, Olha M, Guan, Xiaoquan, Wu, Yuejin, Joiner, Mei-ling, Gao, Zhan, Chen, Biyi, Grumbach, Isabella M, Luczak, Elizabeth D, Colbran, Roger J, Song, Long-Sheng, Hund, Thomas J, Mohler, Peter J, Anderson, Mark E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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