Effects of nifedipine and interleukin-1a on the expression of collagen, matrix metalloproteinase-1, and tissue inhibitor of metalloproteinase-1 in human gingival fibroblasts

Background and Objective:Nifedipine-induced gingival overgrowth is known to be characterized by fibrosis and some degree of inflammation. However, the molecular mechanism of the fibrosis is not fully understood. The purpose of this study was to investigate in vitro the effects of nifedipine and inte...

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Veröffentlicht in:Journal of periodontal research 2006-08, Vol.41 (4), p.266-272
Hauptverfasser: Sakagami, G, Sato, E, Sugita, Y, Kosaka, T, Kubo, K, Maeda, H, Kameyama, Y
Format: Artikel
Sprache:eng
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