Challenges for modeling global gene regulatory networks during development: Insights from Drosophila

Development is regulated by dynamic patterns of gene expression, which are orchestrated through the action of complex gene regulatory networks (GRNs). Substantial progress has been made in modeling transcriptional regulation in recent years, including qualitative “coarse-grain” models operating at t...

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Veröffentlicht in:	Developmental biology 2010-04, Vol.340 (2), p.161-169
Hauptverfasser:	Wilczynski, Bartek, Furlong, Eileen E.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CRMs Developmental networks Drosophila Drosophila - genetics Drosophila - metabolism Gene expression Gene Expression Regulation, Developmental Gene regulatory networks Gene Regulatory Networks - genetics Gene Regulatory Networks - physiology Modeling Models, Genetic Transcription Factors - genetics Transcription Factors - metabolism Transcriptional networks
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