Glutathione accumulation in ethanol-stat fed-batch culture of Saccharomyces cerevisiae with a switch to cysteine feeding

Shot-wise supplementation of cysteine to a yeast culture is a common means of promoting glutathione (GSH) production. In the present work, we study the accumulation kinetics of cysteine, γ-glutamylcysteine, and GSH and the expression of genes involved in GSH and sulfur metabolism in ethanol-stat fed...

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Veröffentlicht in:Applied microbiology and biotechnology 2010-06, Vol.87 (1), p.175-183
Hauptverfasser: Nisamedtinov, Ildar, Kevvai, Kaspar, Orumets, Kerti, Rautio, Jari J, Paalme, Toomas
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Sprache:eng
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