In Vitro Antifungal Activities of D11-2040, a b-1,6-Glucan Inhibitor, with or without Currently Available Antifungal Drugs

We recently reported our discovery of small molecule b-1,6-glucan inhibitor named D75-4590 and the anti-Candida activity of its derivatives D11-2040 and D21-6076. In this study, we further evaluated the antifungal profile of D11-2040. It alone strongly inhibited the vegetative growth and/or hyphal d...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2010-01, Vol.33 (2), p.192-197
Hauptverfasser:	Kitamura, Akihiro, Someya, Kazuhiko, Okumura, Ryo, Hata, Masato, Takeshita, Hiroshi, Nakajima, Ryohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus fumigatus Candida Cryptococcus neoformans
Online-Zugang:	Volltext
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