The STE group kinase SepA controls cleavage furrow formation in Dictyostelium

During a REMI screen for proteins regulating cytokinesis in Dictyostelium discoideum we isolated a mutant forming multinucleate cells. The gene affected in this mutant encoded a kinase, SepA, which is an ortholog of Cdc7, a serine‐threonine kinase essential for septum formation in Schizosaccharomyce...

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Veröffentlicht in:	Cell motility and the cytoskeleton 2009-11, Vol.66 (11), p.929-939
Hauptverfasser:	Müller-Taubenberger, Annette, Ishikawa-Ankerhold, Hellen C., Kastner, Peter M., Burghardt, Emmanuel, Gerisch, Günther
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - metabolism Actins - ultrastructure Animals Cell Cycle Proteins - genetics Cell Surface Extensions - ultrastructure centrosome Centrosome - metabolism Centrosome - ultrastructure Centrosomes Cortex Cortex (temporal) Cytokinesis Cytokinesis - physiology Cytoskeleton Data processing Dictyostelium - chemistry Dictyostelium - ultrastructure Dictyostelium discoideum Interphase Microscopy, Confocal mitosis Nuclear division Nuclei Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Protein-serine/threonine kinase Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins - genetics Septum Spindle Apparatus - physiology Spindle Apparatus - ultrastructure Spindles
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