Induction and maintenance therapy for lupus nephritis: a systematic review and meta-analysis

The aim of this study was to assess the efficacies and toxicities of immunosuppressive treatments for lupus nephritis (LN) versus cyclophosphamide (CYC). A meta-analysis was performed to determine treatment efficacy and toxicity outcomes between mycophenolate mofetil (MMF) and CYC induction therapie...

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Veröffentlicht in:	Lupus 2010-05, Vol.19 (6), p.703-710
Hauptverfasser:	Lee, YH, Woo, J-H., Choi, SJ, Ji, JD, Song, GG
Format:	Artikel
Sprache:	eng
Schlagworte:	Amenorrhea Azathioprine - adverse effects Azathioprine - therapeutic use Bias Clinical trials Cyclophosphamide - adverse effects Cyclophosphamide - therapeutic use Drug dosages Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Induction therapy Infections Internal medicine Kidney diseases Leukopenia Lupus Lupus Nephritis - drug therapy Lupus Nephritis - prevention & control Medicine Meta-analysis Mortality Mycophenolic Acid - adverse effects Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Randomized Controlled Trials as Topic Recurrence Remission (Medicine) Remission Induction Rheumatology Sensitivity and Specificity Systematic review Toxicity Treatment Outcome
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