Spontaneous Ganglioneuroma Possibly Originating from the Trigeminal Ganglion in a B6C3F1 Mouse

In a carcinogenicity study, a neuronal tumor in the cranial cavity was observed in a 110-week-old female B6C3F1 mouse. At necropsy, the tumor was seen at the site of the pituitary gland. Histologically, the tumor consisted of well-differentiated ganglion cells, nerve fiber/neuropil-like elements and...

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Veröffentlicht in:	Toxicologic pathology 2009-04, Vol.37 (3), p.343-347
Hauptverfasser:	Yasui, Yuzo, Ohta, Yasufumi, Ueda, Yoshihide, Hasegawa, Kazushige, Kihara, Tohru, Hosoi, Masayo, Miyajima, Rumiko, Shiga, Atsushi, Imai, Kiyoshi, Toyoda, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chromogranin A - metabolism Female Ganglioneuroma - chemistry Ganglioneuroma - pathology Ganglioneuroma - veterinary Glial Fibrillary Acidic Protein - metabolism Immunohistochemistry Medical sciences Mice Mice, Inbred Strains Neurofilament Proteins - metabolism Neurology Nissl Bodies - chemistry Peripheral Nervous System Neoplasms - chemistry Peripheral Nervous System Neoplasms - pathology Peripheral Nervous System Neoplasms - veterinary Phosphopyruvate Hydratase - metabolism Rodent Diseases - metabolism Rodent Diseases - pathology S100 Proteins - metabolism Synaptophysin - metabolism Toxicology Trigeminal Ganglion - pathology Tumors of the nervous system. Phacomatoses
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