Eosinophils Are Required for the Induction of Bronchial Hyperresponsiveness in a Th Transfer Model of BALB/c Background

Background: Helper T (Th) cells are deeply involved in the pathophysiology of bronchial asthma, such as eosinophilic inflammation, bronchial hyperresponsiveness (BHR), airflow limitation and remodeling. It is still unclear whether Th cells contribute to BHR independently of eosinophilic inflammation...

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Veröffentlicht in:	International archives of allergy and immunology 2010-01, Vol.152 (Suppl 1), p.79-82
Hauptverfasser:	Ohtomo, Takayuki, Kaminuma, Osamu, Yamada, Junji, Kitamura, Noriko, Abe, Akemi, Kobayashi, Noriaki, Suko, Matsunobu, Mori, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Resistance - drug effects Airway Resistance - immunology Allergies Animals Asthma Asthma - immunology Asthma - physiopathology Biological and medical sciences Bronchial Hyperreactivity - immunology Bronchial Hyperreactivity - physiopathology Bronchial Provocation Tests Bronchoalveolar Lavage Fluid - cytology Cell Count Cellular biology Chronic obstructive pulmonary disease, asthma Eosinophils - cytology Eosinophils - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology GATA1 Transcription Factor - genetics Immunology Immunopathology Leukocytes Lymphocytes Lymphocytes - cytology Macrophages - cytology Medical sciences Methacholine Chloride - pharmacology Mice Mice, Inbred BALB C Mice, Mutant Strains Monocytes - cytology Neutrophils - cytology Original Paper Ovalbumin - administration & dosage Ovalbumin - immunology Pneumology Respiratory system Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Helper-Inducer - transplantation
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