Clinical Performance of JAK2 V617F Mutation Detection Assays in a Molecular Diagnostics Laboratory: Evaluation of Screening and Quantitation Methods

The presence of the JAK2 V617F mutation is now part of clinical diagnostic algorithms, and JAK2 status is routinely assessed when BCR/ABL- chronic myeloproliferative neoplasms (MPNs) are suspected. The aim of this study was to evaluate performance of 3 screening and 1 quantitative method for JAK2 V6...

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Veröffentlicht in:	American journal of clinical pathology 2009-11, Vol.132 (5), p.713-721
Hauptverfasser:	CANKOVIC, Milena, WHITELEY, Lisa, HAWLEY, Robert C, ZARBO, Richard J, CHITALE, Dhananjay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Female Humans Investigative techniques, diagnostic techniques (general aspects) Janus Kinase 2 - genetics Male Medical sciences Middle Aged Myeloproliferative Disorders - diagnosis Myeloproliferative Disorders - genetics Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Point Mutation Polymerase Chain Reaction - methods Reagent Kits, Diagnostic Sensitivity and Specificity Young Adult
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