Volar Melanotic Macules
Asymptomatic light brown or tannish‐gray macules are seen on palms and/or soles of black patients, and occsionally on the volar surfaces of whites. They may be mistaken for lesions of secondary syphilis or other postinflammatory hyperpigmented dermatoses. Histologic examination of 14 specimens obtai...
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Veröffentlicht in: | International journal of dermatology 1979-04, Vol.18 (3), p.222-225 |
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creator | Chapel, Thomas A. Taylor, Robert M. Pinkus, Hermann |
description | Asymptomatic light brown or tannish‐gray macules are seen on palms and/or soles of black patients, and occsionally on the volar surfaces of whites. They may be mistaken for lesions of secondary syphilis or other postinflammatory hyperpigmented dermatoses. Histologic examination of 14 specimens obtained at necropsy showed purely epidermal hyperpigmentation of all epidermal layers; or β) melanin restricted to large dendritic melanocytes without appreciable transfer to keratinocytes. The number of melanocytes was not significantly increased, and with one exception, there were no nevus cells. These volar melanotic macules have close clinical and histologic resemblance to melanotic macules observed occasionally on the vermillion area of the lips. |
doi_str_mv | 10.1111/ijd.1979.18.3.222 |
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They may be mistaken for lesions of secondary syphilis or other postinflammatory hyperpigmented dermatoses. Histologic examination of 14 specimens obtained at necropsy showed purely epidermal hyperpigmentation of all epidermal layers; or β) melanin restricted to large dendritic melanocytes without appreciable transfer to keratinocytes. The number of melanocytes was not significantly increased, and with one exception, there were no nevus cells. These volar melanotic macules have close clinical and histologic resemblance to melanotic macules observed occasionally on the vermillion area of the lips.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/ijd.1979.18.3.222</identifier><identifier>PMID: 457315</identifier><language>eng</language><publisher>England</publisher><subject>Adult ; Aged ; Female ; Foot - pathology ; Foot Dermatoses - pathology ; Hand - pathology ; Hand Dermatoses - pathology ; Humans ; Male ; Melanosis - pathology ; Middle Aged ; Skin - pathology ; Treponema pallidum</subject><ispartof>International journal of dermatology, 1979-04, Vol.18 (3), p.222-225</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4472-dda1c1af1591267f9dcfd73c55e773cbfc19dee6abb12a2998f1710eafd6f6b03</citedby><cites>FETCH-LOGICAL-c4472-dda1c1af1591267f9dcfd73c55e773cbfc19dee6abb12a2998f1710eafd6f6b03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijd.1979.18.3.222$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijd.1979.18.3.222$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/457315$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chapel, Thomas A.</creatorcontrib><creatorcontrib>Taylor, Robert M.</creatorcontrib><creatorcontrib>Pinkus, Hermann</creatorcontrib><title>Volar Melanotic Macules</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Asymptomatic light brown or tannish‐gray macules are seen on palms and/or soles of black patients, and occsionally on the volar surfaces of whites. They may be mistaken for lesions of secondary syphilis or other postinflammatory hyperpigmented dermatoses. Histologic examination of 14 specimens obtained at necropsy showed purely epidermal hyperpigmentation of all epidermal layers; or β) melanin restricted to large dendritic melanocytes without appreciable transfer to keratinocytes. The number of melanocytes was not significantly increased, and with one exception, there were no nevus cells. These volar melanotic macules have close clinical and histologic resemblance to melanotic macules observed occasionally on the vermillion area of the lips.</description><subject>Adult</subject><subject>Aged</subject><subject>Female</subject><subject>Foot - pathology</subject><subject>Foot Dermatoses - pathology</subject><subject>Hand - pathology</subject><subject>Hand Dermatoses - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Melanosis - pathology</subject><subject>Middle Aged</subject><subject>Skin - pathology</subject><subject>Treponema pallidum</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtLw0AQxhfxVatnETz0JF4Sd_aZBS9SX5UWL-p12ewDUlJTsw3S_94NKR51LsPMfN_H8EPoAnAOqW6qpctBSZVDkdOcELKHRkAFz5igZB-NMAbIFObqGJ3EuEwjJcCO0CHjkgIfofOPpjbtZOFr89lsKjtZGNvVPp6ig2Dq6M92fYzeHx_eps_Z_PVpNr2bZ5YxSTLnDFgwAbgCImRQzgYnqeXcy9TKYEE574UpSyCGKFUEkIC9CU4EUWI6RldD7rptvjofN3pVRevr9I5vuqglE8CAqiS8_lMIhZQFwYT3Uhiktm1ibH3Q67ZamXarAesem07YdI8tuTTVCVvyXO7iu3Ll3a9j4JTOt8P5u6r99v88PXu57xdQ0D79B77VeP8</recordid><startdate>197904</startdate><enddate>197904</enddate><creator>Chapel, Thomas A.</creator><creator>Taylor, Robert M.</creator><creator>Pinkus, Hermann</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>197904</creationdate><title>Volar Melanotic Macules</title><author>Chapel, Thomas A. ; Taylor, Robert M. ; Pinkus, Hermann</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4472-dda1c1af1591267f9dcfd73c55e773cbfc19dee6abb12a2998f1710eafd6f6b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Female</topic><topic>Foot - pathology</topic><topic>Foot Dermatoses - pathology</topic><topic>Hand - pathology</topic><topic>Hand Dermatoses - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Melanosis - pathology</topic><topic>Middle Aged</topic><topic>Skin - pathology</topic><topic>Treponema pallidum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chapel, Thomas A.</creatorcontrib><creatorcontrib>Taylor, Robert M.</creatorcontrib><creatorcontrib>Pinkus, Hermann</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chapel, Thomas A.</au><au>Taylor, Robert M.</au><au>Pinkus, Hermann</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Volar Melanotic Macules</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>1979-04</date><risdate>1979</risdate><volume>18</volume><issue>3</issue><spage>222</spage><epage>225</epage><pages>222-225</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><abstract>Asymptomatic light brown or tannish‐gray macules are seen on palms and/or soles of black patients, and occsionally on the volar surfaces of whites. They may be mistaken for lesions of secondary syphilis or other postinflammatory hyperpigmented dermatoses. Histologic examination of 14 specimens obtained at necropsy showed purely epidermal hyperpigmentation of all epidermal layers; or β) melanin restricted to large dendritic melanocytes without appreciable transfer to keratinocytes. The number of melanocytes was not significantly increased, and with one exception, there were no nevus cells. These volar melanotic macules have close clinical and histologic resemblance to melanotic macules observed occasionally on the vermillion area of the lips.</abstract><cop>England</cop><pmid>457315</pmid><doi>10.1111/ijd.1979.18.3.222</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Wiley Journals |
subjects | Adult Aged Female Foot - pathology Foot Dermatoses - pathology Hand - pathology Hand Dermatoses - pathology Humans Male Melanosis - pathology Middle Aged Skin - pathology Treponema pallidum |
title | Volar Melanotic Macules |
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