Platelet Aggregation Induced by Ultrasound Under Specialized Conditions in vitro
Human platelets were induced by 2.1-megahertz ultrasound to form aggregates around gas-filled pores in membranes immersed in platelet-rich plasma. The spatial peak intensities required were only about 16 to 32 milliwatts per square centimeter. Ultrasound generated by a medical Doppler device, whose...
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1979-08, Vol.205 (4405), p.505-507 |
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creator | Miller, Douglas L. Nyborg, W. L. Whitcomb, C. C. |
description | Human platelets were induced by 2.1-megahertz ultrasound to form aggregates around gas-filled pores in membranes immersed in platelet-rich plasma. The spatial peak intensities required were only about 16 to 32 milliwatts per square centimeter. Ultrasound generated by a medical Doppler device, whose intensity exceeded this, induced aggregate formation under the same conditions. |
doi_str_mv | 10.1126/science.451616 |
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L. ; Whitcomb, C. C.</creator><creatorcontrib>Miller, Douglas L. ; Nyborg, W. L. ; Whitcomb, C. C.</creatorcontrib><description>Human platelets were induced by 2.1-megahertz ultrasound to form aggregates around gas-filled pores in membranes immersed in platelet-rich plasma. The spatial peak intensities required were only about 16 to 32 milliwatts per square centimeter. Ultrasound generated by a medical Doppler device, whose intensity exceeded this, induced aggregate formation under the same conditions.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.451616</identifier><identifier>PMID: 451616</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Aggregation ; Blood platelets ; Blood Platelets - radiation effects ; Blood Platelets - ultrastructure ; Cavitation flow ; Cell aggregates ; Cell aggregation ; Humans ; Male ; Medical ultrasonics ; Microscopy, Electron, Scanning ; P branes ; Photomicrographs ; Platelet aggregation ; Platelet Aggregation - radiation effects ; Platelets ; String theory ; Transducers ; Ultrasonics ; Ultrasonics in medicine ; Ultrasonography</subject><ispartof>Science (American Association for the Advancement of Science), 1979-08, Vol.205 (4405), p.505-507</ispartof><rights>Copyright 1979 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c291t-89d7129aa7f947f9842c34f25a866de49c654c458c4cc61458485a8338bf7ef83</citedby><cites>FETCH-LOGICAL-c291t-89d7129aa7f947f9842c34f25a866de49c654c458c4cc61458485a8338bf7ef83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1748476$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1748476$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2882,2883,27923,27924,58016,58249</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/451616$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miller, Douglas L.</creatorcontrib><creatorcontrib>Nyborg, W. L.</creatorcontrib><creatorcontrib>Whitcomb, C. C.</creatorcontrib><title>Platelet Aggregation Induced by Ultrasound Under Specialized Conditions in vitro</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Human platelets were induced by 2.1-megahertz ultrasound to form aggregates around gas-filled pores in membranes immersed in platelet-rich plasma. The spatial peak intensities required were only about 16 to 32 milliwatts per square centimeter. Ultrasound generated by a medical Doppler device, whose intensity exceeded this, induced aggregate formation under the same conditions.</description><subject>Aggregation</subject><subject>Blood platelets</subject><subject>Blood Platelets - radiation effects</subject><subject>Blood Platelets - ultrastructure</subject><subject>Cavitation flow</subject><subject>Cell aggregates</subject><subject>Cell aggregation</subject><subject>Humans</subject><subject>Male</subject><subject>Medical ultrasonics</subject><subject>Microscopy, Electron, Scanning</subject><subject>P branes</subject><subject>Photomicrographs</subject><subject>Platelet aggregation</subject><subject>Platelet Aggregation - radiation effects</subject><subject>Platelets</subject><subject>String theory</subject><subject>Transducers</subject><subject>Ultrasonics</subject><subject>Ultrasonics in medicine</subject><subject>Ultrasonography</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkM1L7DAUxYP4NX5sXbnoys2jY9KkabocBt97gqCgsw6Z9LZEMsmYpKL-9UY6KLi43Avndy6Hg9AFwXNCKn4dtQGnYc5qwgnfQzOC27psK0z30QxjykuBm_oYncT4jHHWWnqEDid6hh4erEpgIRWLYQgwqGS8K25dN2roivV7sbIpqOhH1xUr10EoHregjbLmI-tL7zrz5YiFccWrScGfoYNe2Qjnu32KVn9vnpb_y7v7f7fLxV2pq5akUrRdQ6pWqaZvWR7BKk1ZX9VKcN4BazWvmWa10ExrTvLBRNYoFeu-gV7QU3Q1_d0G_zJCTHJjogZrlQM_RtkwnusRLIN_JnBQFqRx2rsEb0l7a2EAmUMt7-WCUMYpJZmeT7QOPsYAvdwGs1HhXRIsv_qWu77l1GA2XO5yjOsNdN_4b_k5Jh9-njVMsIbTTygnhUc</recordid><startdate>19790803</startdate><enddate>19790803</enddate><creator>Miller, Douglas L.</creator><creator>Nyborg, W. L.</creator><creator>Whitcomb, C. C.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19790803</creationdate><title>Platelet Aggregation Induced by Ultrasound Under Specialized Conditions in vitro</title><author>Miller, Douglas L. ; Nyborg, W. L. ; Whitcomb, C. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c291t-89d7129aa7f947f9842c34f25a866de49c654c458c4cc61458485a8338bf7ef83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Aggregation</topic><topic>Blood platelets</topic><topic>Blood Platelets - radiation effects</topic><topic>Blood Platelets - ultrastructure</topic><topic>Cavitation flow</topic><topic>Cell aggregates</topic><topic>Cell aggregation</topic><topic>Humans</topic><topic>Male</topic><topic>Medical ultrasonics</topic><topic>Microscopy, Electron, Scanning</topic><topic>P branes</topic><topic>Photomicrographs</topic><topic>Platelet aggregation</topic><topic>Platelet Aggregation - radiation effects</topic><topic>Platelets</topic><topic>String theory</topic><topic>Transducers</topic><topic>Ultrasonics</topic><topic>Ultrasonics in medicine</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miller, Douglas L.</creatorcontrib><creatorcontrib>Nyborg, W. L.</creatorcontrib><creatorcontrib>Whitcomb, C. C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miller, Douglas L.</au><au>Nyborg, W. L.</au><au>Whitcomb, C. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Platelet Aggregation Induced by Ultrasound Under Specialized Conditions in vitro</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1979-08-03</date><risdate>1979</risdate><volume>205</volume><issue>4405</issue><spage>505</spage><epage>507</epage><pages>505-507</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Human platelets were induced by 2.1-megahertz ultrasound to form aggregates around gas-filled pores in membranes immersed in platelet-rich plasma. The spatial peak intensities required were only about 16 to 32 milliwatts per square centimeter. Ultrasound generated by a medical Doppler device, whose intensity exceeded this, induced aggregate formation under the same conditions.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>451616</pmid><doi>10.1126/science.451616</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
subjects | Aggregation Blood platelets Blood Platelets - radiation effects Blood Platelets - ultrastructure Cavitation flow Cell aggregates Cell aggregation Humans Male Medical ultrasonics Microscopy, Electron, Scanning P branes Photomicrographs Platelet aggregation Platelet Aggregation - radiation effects Platelets String theory Transducers Ultrasonics Ultrasonics in medicine Ultrasonography |
title | Platelet Aggregation Induced by Ultrasound Under Specialized Conditions in vitro |
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